Lege Artis Medicinae

[H2 test for diagnosis of bacterial overgrowth in chronic pancreatitis ]

BALGHA Valéria1, BERGER Zoltán1, PAP Ákos1

MAY 26, 1993

Lege Artis Medicinae - 1993;3(05)

[ Increasing H2, content of exhaled alveolar air is the indicator of small bowel dysbacteriosis. 43 patients with chronic pancreatitis were examined by H2 test using lactulose and lactose loading. Increased content has been found in 32.6% of cases. In patients with alcoholic chronic pancreatitis bacterial overgrowth was somewhat more frequent, than in nonalcoholic cases. There was more bacterial over growth in non-calcifying than calcifying, in non-diabetic than diabetic, and in non-insulin requiring, than insulin requiring groups, although these differences were not significant. Extended abdominal operations and pancreatic surgery did not influence frequency of bacterial overgrowth. In patients with mild or moderate pancreatic insufficiency, however bacterial overgrowth was significantly more common than in patients with severe chronic pancreatitis. Symptoms of chronic pancreatitis generally attributed to pancreatic insufficiency and meteorism might be caused more by the well treatable bacterial overgrowth, than by pancreatic insufficiency itself. ]

AFFILIATIONS

  1. Fővárosi Önkormányzat Szent Imre Kórháza, II. Belgyógyászat Budapest

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