[Creation of fingers]
KOVÁCS Sándor
DECEMBER 19, 2023
Lege Artis Medicinae - 2023;33(12)
KOVÁCS Sándor
DECEMBER 19, 2023
Lege Artis Medicinae - 2023;33(12)
Szöveg nagyítása:
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Lege Artis Medicinae
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Lege Artis Medicinae
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Lege Artis Medicinae
[In the Laboratory of Systems Neuroscience of the Institute of Experimental Medicine, our main objective is the better understanding of the brain mechanisms of cognitive functions. We investigate the nervous system basis of learning, memory, attention and decision-making not only in normal conditions but also in pathological ones, especially concerning the neurodegenerative dementias such as Alzheimer’s and Parkinson’s disease.
Our main profile is conducting animal studies, but we carry out human research too in collaboration with clinical partners. We analyse multichannel, i.e. multidimensional electrophysiological signals using both classical and modern statistical methods and new and powerful machine learning algorithms.
This study presents the activity of our team, while focusing on artificial intelligence applications.
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Lege Artis Medicinae
[By nearing death, patients face more difficulties as they confront with their own transience, with ultimate loss of their life. Among all multidimensional needs of dying people, end-of-life spirituality has received increasing attention in scientific research during the recent decades. The aim of this study is mapping the impact of end-of-life spirituality on the quality of life as reflected in the relevant literature, and to present the scientifically significant key definitions and measurement options by their difficulties.
Review of English-language papers published after 2017, searched in PubMed and PsycINFO databases using the PRISMA-ScR protocol, with scoping review method, that investigate the impact of end-of-life spirituality. In addition, there was also supervised a review of the authors’ unpublished literature review on the same topic conducted in 2016.
A total of 59 articles were identified by the database searches. Only 2 of the previous review papers were applied here. Each reviewed paper was generally positive about the impact of end-of-life spirituality on the quality of life. Two papers mention a possible negative effect of spirituality on certain factors of the quality of life.
Semantic concerns and measurement difficulties of this topic cause discrepancies in evaluating the study results. Further research of practical spirituality should be valuable to clarify which components may cause negative coping experience in the patients.]
Journal of Nursing Theory and Practice
[On the occasion of the 75th anniversary of the founding of the World Health Organization, it is time to examine the circumstances of its creation. Based on sources from contemporary articles, the events present the story of the merger of several smaller national health organizations into one, which formed the World Health Organization known and operating today, the WHO.]
Clinical Neuroscience
To analyze the utility of median nerve (MN) to ulnar nerve (UN) comparative parameters on the diagnosis of carpal tunnel syndrome (CTS) in diabetic patients with distal symmetrical sensorimotor polyneuropathy (DSMPNP).
Clinical Neuroscience
Neuralgic amyotrophy (NA), also known as Parsonage-Turner syndrome or idiopathic brachial plexopathy, is a multifocal inflammatory neuropathy that usually affects the upper limbs. The classic picture is a patient with acute onset of asymmetric upper extremity symptoms, excruciating pain, rapid onset of multifocal paresis often involving winged scapula, and a monophasic course of the disease.
Clinical Neuroscience
[Body mass index (BMI) is positively correlated with the frequency of carpal tunnel syndrome (CTS). However, there are different types of obesity, and the localization of adipose tissue differs between the genders. In this study, we purposed to investigate whether there was an association between the amount of local adipose tissue thickness and anthropometry in upper extremity with the presence and/or electrophysiological severity of CTS on both genders. ]
Clinical Neuroscience
[Hereditary hemorrhagic teleangiectasia (HHT, Osler-Rendu-Weber disease) is an autosomal dominantly inherited disorder caused by the mutation of several possible genes and characterized by malformations of the arteriovenous system in multiple organs. The clinical diagnosis is based on the Curaçao criteria ((1) spontaneous, recurrent epistaxis; (2) teleangiectasias in characteristic sites (lips, oral cavity, nose, fingers); (3) visceral lesions (gastrointestinal, pulmonary, cerebral, spinal); (4) affected first degree relative). The aim of this study is to present the first genetically confirmed Hungarian case of hereditary hemorrhagic teleangiectasia with multiple ischemic strokes. Our 70-year-old woman has been suffering from severe epistaxis since her childhood and presented gastrointestinal bleeding during her adulthood as well. The characteristic skin lesions developed in the 5th decade of life. She was admitted to our department with loss of consciousness and fluctuating speech and swallowing problems. MRI of the brain supplemented with angiography revealed multiple arteriovenous malformations and multiple subacute ischemic lesions. The EEG demonstrated slowing of electric activity in the left frontal lobe. The neuropsychological assessment showed deficits in anterograde memory and executive functions. The diagnostic work-up for other characteristic alterations identified an arteriovenous malformation in the left lung. The genetic analysis demonstrated a heterozygous mutation in the 7th exon of the ENG gene at position 834 resulting in a thymine duplication and an early stop codon by a frame shift. The present case is largely similar to those already described in literature and draws the attention to the importance of multidisciplinary collaboration in the care of HHT patients.]
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Clinical Neuroscience
[Headache registry in Szeged: Experiences regarding to migraine patients]2.
Clinical Neuroscience
[The new target population of stroke awareness campaign: Kindergarten students ]3.
Clinical Neuroscience
Is there any difference in mortality rates of atrial fibrillation detected before or after ischemic stroke?4.
Clinical Neuroscience
Factors influencing the level of stigma in Parkinson’s disease in western Turkey5.
Clinical Neuroscience
[The effects of demographic and clinical factors on the severity of poststroke aphasia]1.
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