Lege Artis Medicinae

[Antibody deficiencies, investigation, therapy]

MOSDÓSI Bernadett, NYUL Zoltán

APRIL 20, 2014

Lege Artis Medicinae - 2014;24(04)

[Inborn antibody deficiencies represent the most common primary immunodeficiency diseases. This heterogeneous group of disorders is characterised by insufficient antibody production resulting from a genetic defect of B cell differentiation or from abnormal interactions between B and T cells. The clinical manifestations are recurrent, often severe upper and lower respiratory tract infections, but chronic diarrhea and autoimmune diseases might also occur. Timely diagnosis and therapy significantly decrease morbidity, thus increasing life expectancy and improve quality of life.]

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