[The author reviews the interventional radiological methods applicable in tumour therapy. The therapy of non-resectable primary and secondary liver tumours is discussed based on literature data and own experience. The possibilities of percutaneous tumour ablation are limited by the size and number of the tumours. Intra-arterial chemotherapy, chemoembolisation and feeding artery occlusion can be successful resulting in longer life and better quality of life in cases with advanced tumours. The results are better if these methods are combined with systemic chemotherapy.]

[There has been increasing expectation in hormone replacement therapy (HRT) as a potentially useful preventive intervention. Observational studies indicated 50% relative risk reduction on ischaemic heart disease among current HRT users. Unfortunately, this has not been justified by the results of the large scale, prospective, placebo controlled, double blind secondary prevention trials. Even these trials underscored the potential adverse effects of hormone replacement therapy (thromboembolic complications, gall bladder disease). No results of completed primary prevention trials are available for the moment. Based on these data the AHA/ACC Science Advisory of 2001 recommends: HRT should not be recommended for secondary prevention There are insufficient data to suggest that HRT should be initiated for the sole purpose of primary prevention of cardiovascular diseases.]