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Pharmacy

Clinical Neuroscience

JANUARY 30, 2024

[Association of upper extremity anthropometry and subcutaneus adipose tissue with carpal tunnel syndrome]

DAROL Sarica Elif, ÇİÇEKLİ Esen , SAYAN Saadet , KOTAN Dilcan , ALEMDAR Murat

[Body mass index (BMI) is positively correlated with the frequency of carpal tunnel syndrome (CTS). However, there are different types of obesity, and the localization of adipose tissue differs between the genders. In this study, we purposed to investigate whether there was an association between the amount of local adipose tissue thickness and anthropometry in upper extremity with the presence and/or electrophysiological severity of CTS on both genders. ]

Clinical Neuroscience

JANUARY 30, 2024

Comparison of pre-mortem 2D-3D ultrasound examination to post-mortem micro-CT of carotid arteries – first experiences

SZEGEDI István , SZABÓ András Dániel , EMRI Miklós , BÉRESOVA Mónika , NAGY Mariann , MOLNÁR Sarolta , NAGY Attila , BERÉNYI Ervin , OLÁH László , CSIBA László

A prerequisite for the treatment of carotid atherosclerosis is the accurate measurement of the stenosis, that is most commonly evaluated by duplex ultrasonography. In this study, we aimed to verify the reliability of 2D and 3D ultrasonography, comparing the data to results of post-mortem micro-CT examination. Neurological patients with any life-threatening, presumably fatal neurological disease were enrolled.

Clinical Neuroscience

JANUARY 30, 2024

Factors affecting long-term prognosis in adult patients with psychogenic non-epileptic seizures

MELIHA TURKSEVER, BABURHAN GULDIKEN, HULYA OZKAN, MERVE Melodi CAKAR

Among epileptic patients who are monitored using the video-electroencephalography monitoring (VEM) technique, in some patients a psychogenic non-epileptic seizure (PNES) can be identified as a definitive diagnosis. The longterm prognosis of these patients is not well known. In this study, we aimed to determine the factors that affect the prognosis of PNES. Forty-one PNES patients diagnosed using VEM between 2012 and 2022

Clinical Neuroscience

JANUARY 30, 2024

Glioblastoma epigenomics discloses a complex biology and potential therapeutic targets

KRABÓTH Zoltán , TOMPA Márton , URBÁN Péter , GÁLIK Bence , KAJTÁR Béla , GYENESEI Attila , KÁLMÁN Bernadette

Glioblastoma (GBM), a highly aggressive form of brain tumors, has been extensively studied using OMICS methods, and the most characteristic molecular determinants have been incorporated into the histopathological diagnosis. Research data, nevertheless, only partially have been adopted in clinical practice. Here we aimed to present results of our epigeno­ mic GBM profiling to better understand early and late determinants of these tumors, and to share main elements of our findings with practicing professionals.

Clinical Neuroscience

JANUARY 30, 2024

MRI radiomics based machine learning model of the periaqueductal gray matter in migraine patients

MESE Ismail , KARACI Rahsan , ALTINTAS TASLICAY Ceylan , TASLICAY Cengizhan , AKANSEL Gur , DOMAC Fusun Saime

The aim of the study was to investigate the question: Can MRI radiomics analysis of the periaqueductal gray region elucidate the pathophysiological mechanisms underlying various migraine subtypes, and can a machine learning model using these radiomics features accurately differentiate between migraine patients and healthy individuals, as well as between migraine subtypes, including atypical cases with overlapping symptoms?

Clinical Neuroscience

JANUARY 30, 2024

Study protocol of the Hungarian Longitudinal Study of Healthy Brain Aging (HuBA)

BANKÓ M. Éva , WEISS Béla , HEVESI István , MANGA Annamária , VAKLI Pál , HAVADI-NAGY Menta , KELEMEN Rebeka , SOMOGYI Eszter , HOMOLYA István , BIHARI Adél , SIMON Ádám , NÁRAI Ádám , TÓTH Krisztina , BÁTHORI Noémi , TOMACSEK Vivien , HORVÁTH András , KAMONDI Anita , RACSMÁNY Mihály, DÉNES Ádám , SIMOR Péter , KOVÁCS Tibor , HERMANN Petra , VIDNYÁNSZKY Zoltán

Neurocognitive aging and the associated brain diseases impose a major social and economic burden. Therefore, substantial efforts have been put into revealing the lifestyle, the neurobiological and the genetic underpinnings of healthy neurocognitive aging. However, these studies take place almost exclusively in a limited number of highly­developed countries. Thus, it is an important open