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[In the EMPA-REG Outcome trial, it was already observed that cardiovascular (10.5% vs. 12.1%) and renal (1.7% vs. 3.1%) outcomes were better with empagliflozin treatment compared to placebo. The favorable effects of empagliflozin were consistent across the KDIGO risk categories. CVOT trials conducted with other SGLT2 inhibitors also concluded with promising renoprotective results.]
[Both hypertension and andropause alone increase the risk of cardiovascular disease. The incidence of both diseases increases with age. As a consequence they may often present concurrently in men. The damaging effects of the two noxae may add up - this may be observed in the remodeling processes of coronary resistance vessels. This mini-review summarizes the effects of hipertension, testosterone deficiency and the combined effects of these two noxae on the morphological, biomechanical and functional adaptation of coronary resistance vessels, as well as on cardiovascular diseases.]
[Our aim is to analyse venous thromboembolic events regarding chronic kidney disease. Based upon epidemiologic data, both thromboembolic and haemorrhagic events are more frequent among patients with chronic kidney disease. Changes in levels of coagulant factors, thrombocyte and endothel disfunction, uremic toxins and dialysis related issues share role in pathogenesis. Guidelines lack of adequate information regarding this specific patient group. Therapeutic shift can be observed from vitamin K antagontists toward direct oral anticoagulants, not only in general population but also in CKD patients, with special interest in apixaban. Another therapeutic trend is change from unfractioned heparin to low molecular weigh heparins with anti Xa level monitoring among CKD population. Special attention is needed for thrombotic events related to eritropoietin therapy and hemodialysis access.]
[The activity of the autonomic (parasympathetic and sympathetic) nervous system plays a decisive role in the regulation of the circulatory system and in the adaptation of the organism to the ever-changing environmental situation. The equilibrium state of the parasympathetic and sympathetic nervous systems (or its cessation in the case of autonomic dysfunction) determines the heart rate and contractility of the heart muscle. The sympathetic nervous system also plays a decisive role in determining the degree of peripheral vascular resistance. These factors are basic elements for regulating blood pressure. Based on extensive research conducted over the past five decades, the significance of elevated heart rate can be outlined for today’s practicing physicians, especially when assessing cardiovascular risk in hypertensive patients. This brief summary was intended to collect the most important literature data in this regard.]
[ANCA-associated vasculitis is a systemic autoimmune disease with a severe course and a high percentage of renal involvement. It is much more common in the adult population than in children, so there are few large case-control studies in pediatric population. We present case reports of six children treated for ANCA-associated vasculitis over the past five years. In addition to the case presentation, we will also discuss current immunosuppressive therapeutic options and the issue of plasmapheresis. We describe the initial symptoms and the time between the onset of symptoms and diagnosis. We present the initial laboratory data and a 12-month retrospective follow-up of renal function. We also describe the therapies used in our patients. Given the small number of cases, we do not aim to present detailed statistical conclusions.]
[The use of fluorides is one of the most important areas of dental prevention. It has many beneficial effects on teeth, and it is worth using them starting from childhood. It has an important role in caries prevention and in ensuring the strength of the enamel. However, we must pay attention to take fluoride into our body in moderation. If we don’t act accordingly, we can damage the condition of the teeth and the structure of the bones, to which we should pay special attention during childhood. Fluorosis can be prevented by attention, but adequate information is essential for this, which can be provided by both dentists and dental hygienists.]
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Clinical Neuroscience
[Headache registry in Szeged: Experiences regarding to migraine patients]2.
Clinical Neuroscience
[The new target population of stroke awareness campaign: Kindergarten students ]3.
Clinical Neuroscience
Is there any difference in mortality rates of atrial fibrillation detected before or after ischemic stroke?4.
Clinical Neuroscience
Factors influencing the level of stigma in Parkinson’s disease in western Turkey5.
Clinical Neuroscience
[The effects of demographic and clinical factors on the severity of poststroke aphasia]1.
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