Gastroenterology

Lege Artis Medicinae

NOVEMBER 30, 2021

[A practical demonstration of critically assessing health economic analyses]

MERÉSZ Gergô, DÓCZY Veronika, HÖLGYESI Áron, NÉMETH Gergely

[During the critical assessment of health economic analyses, it is useful to present their uncertainties within a standardized framework. The aim of this research is to demonstrate how to use the procedural framework to identify, quantify and interpret such uncertainties through the examples of cell and gene therapies. Based on the review of methodological documents used by the Di­vi­sion of Health Technology Assessment at the National Institute of Pharmacy and Nutrition of Hungary (NIPN), and... tovább »

HUN 2021;31(11)

Clinical Neuroscience

NOVEMBER 30, 2021

[Relationships between COVID-19 disease, nutritional status, and dysphagia, particularly in stroke patients ]

KOVÁCS Andrea, SZABÓ Pál Tamás, FOLYOVICH András

[The new coronavirus, SARS-CoV-2, which causes the COVID-19 disease can lead to severe acute respiratory distress syndrome (ARDS). It poses a serious challenge to the health care system, especially intensive care. Neurological patients, usually of advanced age and with a myriad of comorbidities, are at particular risk through the impact of the new coronavirus on their condition and nutritional capacity. Stroke is a leader in morbidity and mortality data, with a focus on dysphagia and its... tovább »

HUN 2021;74(11-12)

Clinical Neuroscience

NOVEMBER 30, 2021

Parry-Romberg syndrome: is it a “relapsing-remitting” disease?

KAYA TUTAR Nurhan , AKKAS Yazıcı Sinem, OMERHOCA Sami, KALE Nilufer, SAIP Sabahattin

Parry-Romberg syndrome, also known as progressive hemifacial atrophy, is a rare, slowly progressive disorder characterized by unilateral, painless atrophy of the skin and subcutaneous tissue of the face. Neurological manifestations such as epilepsy, migraine and trigeminal neuralgia are relatively common and accompany in 15-20% of cases. Various etiologies such as infection, trauma, embryonic developmental dysfunction, sympathetic dysfunction and autoimmune disorders have been suggested as... tovább »

ENG 2021;74(11-12)

Clinical Neuroscience

NOVEMBER 30, 2021

Rare complication of West Nile viral encephalitis

FARAGÓ Péter , FRICSKA-NAGY Zsanett, KLIVÉNYI Péter , TAJTI János

In our case report, we are presenting a 72 years old male patient. The patient’s symptoms were fever, dizziness, general weakness at the time of admission. The laboratory and CSF tests revealed central nervous system inflammation. West Nile virus was identified from the cerebrospinal fluid. After the symptoms of infection and during supporting treatment, severe, progressing hyponatremia evolved with unknown pathology. According to previous investigations and our diagnostic and therapeutic... tovább »

ENG 2021;74(11-12)

Hypertension and nephrology

NOVEMBER 01, 2021

[Subtype diagnosis, treatment, complications and outcomes of primary aldosteronism and future direction of research: a position statement and consensus of the Working Group on Endocrine Hypertension of the European Society of Hypertension – excerpts]

KOVÁTS Viktória, ALFÖLDI Sándor

[Primary aldosteronism is a frequent cause of secondary hypertension requiring a specific pharmacological treatment with mineralocorticoid receptor antagonist or with unilateral adrenalectomy. These treatments have shown to reduce the excess of cardiovascular risk characteristically associated with this disease. In this consensus, we discussed the procedures for the diagnosis of primary aldosteronism, we address the strategies for the differential diagnosis of primary aldosteronism subtypes and... tovább »

HUN 2021;25(05)

Clinical Neuroscience

SEPTEMBER 30, 2021

[Treatment and new evidences in neuromyelitis optica spectrum disorder ]

ILLÉS Zsolt

[Treatment and new evidences in neuromyelitis optica spectrum disorder Illés Zs, MD, PhD Ideggyogy Sz 2021;74(9–10):309–321. Neuromyelitis optica spectrum disorder (NMOSD) is associated with antibodies against AQP4 in about 80% of the cases. In about one-fourth of seronegative cases, antibodies against the MOG protein are present in the serum (MOG-antibody associated disease, MOGAD). This article discusses off-label azathioprine and mycophenolate mofetil in the treatment of NMOSD and... tovább »

HUN 2021;74(09-10)