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[This study reviews the cardiovascular risk of women with type 1, gestational, and type 2 diabetes.
Research data published so far in this topic have confirmed a number of cardiovascular risk factors, which may cause differences in risk profile between female and male diabetic patients. As soon as recognizing diabetes, we have to concern the patients’ cardioprotective diet, assessment of their cardiovascular risk factors and aiming their therapeutic target values. ]
[Concerning cardiovascular (CV) risk, beside hormonal contraception, menopausal hormone therapy (MHT) has a pre-eminent clinical significance. If women start MHT younger than 60 years of age, or within 10 years after their menopausal transition, the risk of coronary diseases and mortality too decreases. Conventional oral MHT slightly increases the risk of venous thromboembolism (VTE) and stroke, while transdermal admission does not it. MHT initiated in women above 60, raise the risk of cardiovascular (CV) diseases, thus it is useful to start MHT at the onset of menopause syndrome signs (primarily hot flashes), preferably at a younger age. Preventing serious late complications to start and continue MHT at least until natural menopause is essential in premature ovarian insufficiency and early menopause. Below, we summarize the CV implications of MHT and its alternative treatment options.]
[In the course of our research, we compared the pre-pregnancy test mass index of Hungarian women with the results of the National Nutrition and Nutritional Status Examinations.
Our cross-sectional study was conducted between 01.01.2020 and 01.08.2020. During the nonrandom, targeted, expert sample selection, the target group included pregnant women or mothers raising at least one minor child (N=1423). Exclusion criteria include the omission of mandatory questions. Our survey was done online, with a self-filled questionnaire, anonymously. In the questionnaire, we used sociodemographic, anthropometric, pregnancy and nutrition-related questions. The data were analyzed with IBM SPSS 25.0 statistical software, descriptive statistics and tables.
The normal BMI was typical only for those under 20 years of age (21 kg/m2). The largest proportion of people over 20 years of age were overweight (>25 kg/m2). Every fourth pregnant woman (43.4%) and every third mother (33%) reported that excess body weight does not bother them at all.
Based on the body mass index, Hungarian women are already overweight before pregnancy, which entails an increased health and financial burden.]
[Nowadays, the epidemic spread of obesity is mainly linked to changing environmental factors and is a serious public health problem. Obesity alone can be associated with increased mortality, but obesity is also an independent risk factor for several chronic diseases such as diabetes, hypertension and chronic kidney disease which have a major public health burden.]
[Common complications of type 2 diabetes are chronic kidney failure and chronic heart failure. However, chronic renal failure and chronic heart failure can contribute to the development and deterioration of each other, and can be present earlier and more severely in the case of diabetes. Furthermore, type 2 diabetes might also occur more frequently in case of chronic kidney- and heart failure. All of these are often accompanied by atherosclerotic cardiovascular disease and hypertension.]
[In the EMPA-REG Outcome trial, it was already observed that cardiovascular (10.5% vs. 12.1%) and renal (1.7% vs. 3.1%) outcomes were better with empagliflozin treatment compared to placebo. The favorable effects of empagliflozin were consistent across the KDIGO risk categories. CVOT trials conducted with other SGLT2 inhibitors also concluded with promising renoprotective results.]
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