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Lege Artis Medicinae

DECEMBER 10, 2019

[Family medicine as a career. Medical students’ attitudes and vocational choice motivations]

MOHOS András, VARGA Albert, MARKÓ-KUCSERA Mária, KALABAY László, TORZSA Péter

[INTRODUCTION - The large number of vacant general practices is a burning issue in Hungary. The entering of new colleagues into the general practitioner speciality training does not pose a real solution to the human resources crisis in this field. Our aim is to assess medical students’ attitudes and knowledge about general practice. SAMPLE AND METHOD - Cross-sectional survey with self-completed questionnaires at the University of Szeged, with the participation of 94 fourth and fifth year medical students in 2016 and 78 first and fourth year medical students in 2017. RESULTS - In 2016 1% of students planned for sure, and 16% planned probably to work as a general practitioner in the future. In 2017 3.9% of first-year students planned definitely to be a general practitioner, and 15.4% planned that probably. Among fourth-year students 0% of students planned for sure, and 19.2% planned probably to work as a general practitioner in the future. Whatever the presence of family medicine in undergraduate training influenced the medical students’ opinion about the profession positively (0.4-1.3 on a scale based on the direction and strength of the effects of certain factors ranging from -5 to +5). Those who were interested in family medicine considered the situation of healthcare significantly worse (p=0.027), than those who were not interested. To make the profession more attractive the following factors may play the most important role: the more intense presentation (I: 37%) of general practice in undergraduate training, improving the prestige of family medicine (IV: 31%), high-quality work (IV: 39%). CONCLUSIONS - Few medical students plan to work as general practitioner in the future. The most effective way to raise interest in family medicine is to increase the students’ knowledge and awareness of this specialisation, and the more intensive presentation of family medicine in undergraduate training is a key issue.]

Clinical Neuroscience

SEPTEMBER 30, 2019

[The role of epigenetic regulations in early childhood diseases]

TORY Vera

[With the acceptance of “The developmental origins of health and disease” concept in the 1990s, it became clear that epigenetic inheritance, which do not involve changes in the DNA sequence has important role in the pathogenesis of diseases. Epigenetic regulation serves the adaptation to the changing environment and maintains the reproductive fitness even on the drawback of increased risk of diseases in later life. The role of epigenetic mechanisms in chronic non-communicable diseases has been well established. Recent studies have revealed that epigenetic changes have also causal role in certain pediatric diseases. The review evaluates the recent epigenetic findings in the pathomechanism of common pediatric diseases. The wide range and long-lasting duration of epigenetic regulations give importance to the subject. Methods are already available to evaluate a part of the epigenetic changes in the clinical practice, presently aiming primarily the estimation of the disease risk or definition of diagnosis. Furthermore, there are already available limited means to influence the epigenetic regulation. ]

Lege Artis Medicinae

SEPTEMBER 10, 2019

[Working capacity assessment: a literature review]

MÁK Kornél, FEHÉR Gergely, GOMBOS Katalin, PUSCH Gabriella, KOLTAI Katalin, BANK Gyula, KÓSA Gábor, VARJASI Gábor, TIBOLD Antal

[INTRODUCTION - Although work capacity assessment (WCA) has high social and economical impacts, national medical standards are lacking in Hungary. AIM - The aim of our literature search based review was to gather evidence and international standards on WCA. RESULTS - There are different methods in WCA, from questionnaire forms to computer-based evalution, the latter seems to be the most effective. Apart from physical WCA, additional cardiovascular risk profile and psychoscocial evaluations are recommended. Despite of intesive research of the topic, evidence-based standards do not exist. CONCLUSION - There is an increasing demand on evidence-based WCA. ]

Hypertension and nephrology

SEPTEMBER 10, 2019

[Kidney diet and the patient compliance issue ]

LADÁNYI Erzsébet

[There have been significant developments in the field of nephrology and dialysis as for the science and technology are concerned in the past decades. However, CKD patients still show high mortality and morbidity. From among the several factors determining the long-term outcome of CKD patients metabolic disorder and malnutrition play an important role. Malnutrition is often not diagnosed or is not paid enough attention to in the complex treatment of CKD patients. It is important to make both the patients and clinical staff more aware of proper nutrition and importance of prevention and treatment of malnutrition, respectively. The early diagnosis and treatment of malnutrition is of utmost importance in CKD patients. The long term renal failure and the accompanying malnutrition have a negative impact on their long term outcome and quality of life. Since the malnutrition causes a lot of complications, it is indispensable for dietitians and nephrologists to work closely together. Patient compliance is a determining factor in the successful implementation of renal diet.]

Journal of Nursing Theory and Practice

FEBRUARY 28, 2019

[Faces from the Hungarian Nursing Hall of Fame: the exemplary career of Katalin Durgó recipient of the Henry Dunant Meda]

BOROS Károlyné, FEDINECZNÉ VITTAY Katalin, PERKÓ Magdolna, SÖVÉNYI Ferencné

[In this part of their series on outstanding figures in Hungary’s nursing history authors present the life of Ms. Katalin Durgó, a Red Cross volunteer nurse-midwife, whose lifelong services to promote the humanitarian cause of the Red Cross were acknowledged by awarding to her, at the age of 83 years, the Henry Dunant Medal, the highest award of the Red Cross Movement. Ms. Durgó was the 5th awardee globally, the first ever Hungarian recipient and the second person to have been decorated in their lifetimes. Following her self-sacrificing and fearless work in the war theatres of WWI, Ms. Durgó worked as a local midwife in rural Hungary delivering one thousand babies as testified by her Midwife’s birth logbook. She carried out her work with a strong sense of conscientiousness, punctuality, untiring diligence, devotion and solid professional knowledge and skills; her personal and professional lives are shining examples for today’s nursing generation. ]

Journal of Nursing Theory and Practice

FEBRUARY 28, 2019

[Who helps the caregivers? - Psychosocial characteristics of nurses in dementia care ]

STALLER Judit, KOVÁCS Zsuzsanna, PÁLVÖLGYI Miklós

[The aim of the study: Studies underline the increasing burden of dementia people. Hungarian social care system is also facing dementia care challenge. In case of developing of social sector, it is beneficial to research the psychosocial status of nurses working in dementia care. Material and method: N=130 professional caregivers in dementia care filled out self- administered questionnaires. Standardized health-psychological scales were evaluated: SWLS, Rahe’s Life Meaning, Beck’s Inventory of Measuring Depression, Maastricht Vital Exhaustion, Freudenberger’s Burn Out Inventory. Results: Caregivers have fatigue, dissatisfaction and tendency of quitting profession. Scales show high burn-out, exhaustion and depression and show correlations. Depression correlates with vital exhaustion (r=0.549), depression moves with burn out r=0,528. SWLS correlates opposite with Vital Exhaustion: r = - 366. Coherence and SWLS shows statistically significance correlation: r=0,455. Conclusion: Indicators apply nurses are in risk conditions. More focus on workplace satisfaction, psychosocial care and stress management training is essential. .]

Lege Artis Medicinae

JULY 20, 2019

[Gynecological correlations of eating disorders]

GALIGER-DOBOS Kitty, TÚRY Ferenc

[In recent decades, the incidence of eating disorders (its two major forms are anorexia nervosa and bulimia nervosa) has increased, their course has been delayed, and their complications are becoming more frequent and severe. Eating disorders cannot only damage physical and mental health but also affect reproductive health, future mothers and their children. Understanding the biological and psychosocial factors that explain the gynecological conditions related to eating disorders is essential regarding fertility and pregnancy. The present review summarizes data published from 2000 about the gynecological effects of eating disorders. In daily practice, the multidisciplinary collaboration is particularly important to pro­vide women with eating disorders with comprehensive care. The appropriate information of women who plan to have children is essential in order to increase the likelihood of conception and reduce the risk of miscarriage. ]

Clinical Neuroscience

JULY 30, 2019

Cerebral cavernous malformation type 1 with retinal blood vessel tortuosity and KRIT1 gene mutation

KALMÁR Tibor, MARÓTI Zoltán, VADVÁRI Árpád, HALMOSI Ágnes, KÁLOVITS Ferenc, KÁLMÁN Bernadette

Cerebral cavernous malformations (CCMs) represent a relatively rare and heterogeneous clinical entity with mutations identified in three genes. Both sporadic and familial forms have been reported. We present a young female patient with episodic paresthesia and headaches, but without acute neurological deficits. Her mother had a hemorrhaged cavernoma surgically removed 21 years ago. Cranial magnetic resonance imaging revealed multiple cavernous malformations in the size of a few millimeters and the ophthalmologic exam detected retinal blood vessel tortuosity in the proband. Targeted exome sequencing analysis identified a nonsense mutation in exon 16 of the KRIT1 gene, which resulted in a premature stop codon and a truncated protein underlying the abnormal development of cerebral and retinal blood vessels. This mutation with pathogenic significance has been reported before. Our case points to the importance of a thorough clinical and molecular work up despite the uncertain neurological complaints, since life style recommendations, imaging monitoring and genetic counseling may have major significance in the long term health of the patient.

Clinical Neuroscience

JULY 30, 2019

[In Memoriam Mátyás Bobest ]

KUNCZ Ádám

[Mátyás Bobest died in May, 2019, at the age of 79, following a disease tolerated with patience. He was the 1st nominated Chef of the independent Neurosurgical Department at the Markusovszky University Teaching Hospital, Szombathely in 1980, and under his leadership it worked for 23 years. He succeed to create a Neurosurgical Centre of West Hungary with his diligent and ambitious work. Beside his everyday surgical duties he paid attention to the continuing medical education and made research on the intervertebral disc degeneration. ]

Clinical Neuroscience

JULY 30, 2019

Attitude of spine surgeons towards the application of 3D technologies - a survey of AOSpine members

ÉLTES Endre Péter, KISS László, BARTOS Márton, EÖSZE Zsolt, SZÖVÉRFI Zsolt, VARGA Pál Péter, LAZÁRI Áron

Background - 3D technologies (3D virtual and physical model, 3D printing, computer aided engineering, finite element analysis based simulations) play an important role in personalized spine surgery. Objective - In collaboration with AOSpine a global, online survey-based study was performed in order to determine the acceptance rate and the factors which stand against the wider spread of 3D technologies. Methods - A survey containing 21 questions was developed and divided into five pages, every page corresponding to one chapter. Our analysis is based on the responses of 282 spine surgeons from 57 countries. To interpret our results in a global context, we used the Human Development Index of the respondent's countries in comparisons. Results - Significant difference between the AOSpine regions (p ≤ 0.05) was found, with the highest acceptance in Asia-Pacific region. There was no significant difference in acceptance score according to the field of spine surgery, or the surgical experience in years (p=0.77, and p=0.19). In the case of public practice, we found significantly higher acceptance compared to private and mixed (public and private) surgical practice (p ≤ 0.05). The acceptance of the technology varied based on the respondent’s resident country’s Human Development Index and was significantly different between „Medium” vs “Very high” (p = 0.0005) and „High” vs „Very high” (p=0.019) category. Significant positive correlation was found between the acceptance score and the HDI score (Spearman test, ρ = 0.37, p = 0.007). The main limitation factor was identified as the lack of information. Conclusion - There is high interest among spine surgeons towards the incorporation of 3D technologies into the clinical practice. Education, the healthcare system, and the economic environment plays a major role in acceptance. Our results provide the basis of a strategy to promote the application of 3D technologies.