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Journal of Nursing Theory and Practice

FEBRUARY 28, 2016

[The patients with sensory system impairment in peritoneal dialysis]


[The sensory system is responsible for perceiving information, which enables us to connect with the outside world. Its impairment could limit an individual’s chances to an equal role in society. Introduction of a special training programme that provides equal opportunities for patients with disabilities to participate in the peritoneal dialysis (PD) programme. In visually impaired patients training was not based on the visual teaching aids but on verbal communication (constant repetition, questioning). In patients with hearing loss visualisation and dexterity are in focus. Speech impediment, a condition often coexisting with hearing loss, made communication more difficult; therefore the training is built on writing, articulation and sign language. By acquiring the theoretical and technical bases of PD treatment, our patients is able to complete safe solution exchanges in their own homes. Once self-care treatment commenced, their nursing continued on an individual basis. Self-care treatment of PD patients with sensory impairment requires prudence, adequate training and aftercare; however according to our experience it does not necessarily imply a higher occurrence rate of complications. ]

Lege Artis Medicinae

JUNE 20, 2016

[End state AIDS patient at an intensive care unit - a case report with unconventional lessons]

ORTUTAY András, MARJANEK Zsuzsa, NAGY Károly, RÁCZ József, BARCS István

[A 26 year old male patient with unknown medical background had been admitted at the Department of Anestesiology and Intensive Therapy of the Jávorszky Ödön Hospital in the city of Vác. His HIV positivity had been revealed only at the 8th day of his hospitalization. He was living in a small settlement as an i.v. drug user, unknown to the drug prevention system or the STD primary care providing network. Being an end state AIDS patient, the time of the infection, the number of his contact persons, the source of the infection and the previous epidemiological pathway were not known. With this case report we would like to call attention to the importance of the differential diagnosis of AIDS disease, the role of the proper safety regulations concerning potentially infected and infected persons, the epidemiological importance of undiagnosed infections, and the extension of drug prevention services reachable for all persons in need. ]

Clinical Neuroscience

SEPTEMBER 30, 2015

Multimodal quantitative characterization of intracranial epidermoid cysts: preliminary results

HORVÁTH Andrea, NAGY Szilvia Anett, PERLAKI Gábor, ORSI Gergely, BOGNER Péter, DÓCZI Tamás

Background and purpose - The differentiation of epidermoid cysts from other intracranial lesions with CT and conventional MR imaging is challenging. The risk of residual and recurrent disease is high and multimodal imaging should therefore promote a precise differential diagnosis. Since epidermoid cysts are histologically identical to middle ear cholesteatomas, MRI methods that are useful in the diagnosis of cholesteatoma; specifically EPI DWI and a non- EPI diffusion subtype (HASTE DWI) may possibly be applicable to epidermoid cysts. Besides testing the diagnostic utility of these methods on epidermoid cysts, our goal was to quantify the T1 and T2 relaxation times, the ADC values and the magnetization transfer ratios in order to acquire objective, characteristic information about their structure and contents. Finally, our goal was to provide the physician with a reliable, multimodal diagnostic tool that supports accurate surgical planning. Methods - Two patients with epidermoid cysts were examined. Besides the conventional MR scans EPI DWI, HASTE DWI, quantitative T1, T2 and magnetization transfer measurements were performed mappingwith a 3T MR scanner. After image registration, T1, T2 relaxation times and the magnetization transfer ratio inside a ROI were determined according to the lesion location on HASTE DWI. Mean ADC values inside the epidermoid cysts were also calculated by both mono-exponential and bi-exponential diffusion models. Results - Our results revealed relatively high T1 and T2 relaxation times and ADC values, and low magnetization transfer ratios in both subjects. Conclusion - HASTE-DW MRI provides accurate morphologic information on epidermoid cysts, while T1, T2, ADC and magnetization transfer ratio maps are quantitative techniques. Thus the combination of these methods results in a confident preoperative diagnosis and aids to determine the indication of retreatment in the event of recurrence.

Lege Artis Medicinae

SEPTEMBER 22, 2013

[Drug use and death-seeking behaviour attitudes toward death among opiate users]

PAP Ágota, HEGEDÛS Katalin

[Many times, behind mens’ fears there is the fear of death. Drug use can be defined as a kid of self destruction, so it is directly linked to attitudes toward death. In Hungary, suicide among young people is one of the leading causes of death, which is often associated with some kind of addiction or substance abuse. We can also say that drug use is an indirect way of “death search”, which prolongs the agony and the time of suffering. Drug-related death can be directly attributed to drug overdose. Intravenous drug use may cause a risk of infectious diseases (such as sharing needles/syringe/filter use) - HCV, AIDS, etc. Intravenous drug use is mostly - but not exclusively - characteristic to opiate users. Heroin’s mode of action is described as causing an intense feeling of euphoria and a way of feeling augmenting to stupor. Its addictive potential is very high, the degradation is visible and can be fatal. In this paper, we discuss previous observations on overdose that is the validity of harm reduction justified by former research, the possible predictors of overdose and the identification of the prevention area.]

Journal of Nursing Theory and Practice

FEBRUARY 28, 2013

[Preventive strategies applied in decubitus prevention in Hungary and Slovakia]


[The incidence of decubitus ulcers affects nurses working not only in Slovakian hospitals, but those in Hungary too. The proportion of patients with bedsores in a given institution partly depends on the nurses, since improper nursing has a major role in the development of this syndrome. By the same token, a low incidence of pressure ulcers is the best proof of high-quality nursing. The main motivation for the research was to gain an insight into the methods of decubitus prevention applied in the two countries. The purpose of the study was to show the current state of the prevention carried out in the two institutions, how a preventive attitude is instilled, what kind of assessment scale is used, what the protocols contain, what kind of aids are available for us, and how documentation is maintained.]

Journal of Nursing Theory and Practice

JULY 30, 2012

[Impact of post hip-replacement motor functions on the patient’s subjective state of health and perception of surgical success]


[Research aim: The authors analyse the extent to which the change in motor function infl uences the patients’ sense of illness fi ve years after the implantation of an artifi cial hip replacement. Methodology and sample: The retrospective follow-up survey was conducted in the Jávorszky Ödön Hospital in Vác through analysis of the electronic patient database and the returned questionnaires. A total of 109 patients who had received artifi cial hip replacements were included in the survey. The authors analysed the objective motor organ indicators (movement of the hip joint, use of mobility aids) based on the patients’ subjective sense of illness five years after the surgery, and the patients’ opinions about the operation. Results: In the 5th postoperative year the patients’ motor function had signifi cantly improved, and the use of mobility aids had signifi cantly decreased. In terms of the patients’ sense of illness, no signifi cant difference was found between the studied motor organ indicators of those who considered themselves to be healthy and of those who regarded themselves as ill. Conclusions: A successful hip replacement signifi cantly improves the patients’ motor function in the 5th postoperative year, but this has little bearing on the sense of illness. In this period the nursing staff should concentrate on other factors if they want to improve the patients’ quality of life.]


NOVEMBER 10, 2007

[MOOT-COMP study - Compliance of patients with antiporotic treatment]

BORS Katalin, BOROS Erzsébet

[INTRODUCTION - Several studies prove the importance of the lack of compliance in the ineffectiveness of drugs which have been tested by clinical studies. In our study we finded the reasons of leaving off the antiporotic treatment. PATIENTS AND METHODS - 1067 osteoporotic patients (91% women, 9% men) were enrolled to examine compliance and to find explanation of non-compliance. We asked the patients about medications, exercises, electrotherapy and medical aids. RESULTS - Medications were recommended for most patients and exercise was the secondary most common therapeutic method. Electrotherapy was prescribed for one third and medical aids were recommended for one fifth of the recruited patients. Two third of patients reported to take all pills, most of them suffered from bone fracture. More than one fifth of patients sometimes or often forgot to take the treatment. 10% more patients did exercises than it was recommended by the practitioner. However, only 25% of all patients did exercises appropriate frequency and at least 20 minutes per day. Electrotherapy was not prescribed by the doctors for more than half of patients on this treatment. Medical aids were not used by 10% of patients despite the recommendations. Almost one third of the enrolled patients reported a fact which disturbed keeping recommendations of the doctors. These facts were financial problems, long waiting lists and low motivation of patients for keeping recommendations. The compliance did not correlate with education and social status. The patients with multiple fractures were more comply with medications and exercises. CONCLUSION - Drawing the informed patient into decision making and knowing the therapeutic outcome are important factors for keeping therapeutic recommendations. The high fracture rate in Hungary attracts our attention for enhance patient compliance.]

Lege Artis Medicinae

OCTOBER 20, 2004


SOMOGYI Ágota, SZABÓ Tamás, KISHÁZI Péter, KISS Erika, ARATÓ Gabriella, PÁL Katalin, MADÁCSY László

[INTRODUCTION - Intestinal lipodystrophy, Whipple’s disease is an uncommon, chronic, systemic bacterial infection. It occurs predominantly in Caucasian males older than 40 years. The gastrointestinal tract is the most frequently involved organ, with clinical manifestations such as abdominal pain, malabsorption syndrome with diarrhea and weigth loss. Patient may present with low grade fever or fever of unknown origin, arthritis, lymphadenopathy, skin hyperpigmentation, endocarditis, pleuritis and peripheral and central neurological manifestations. Due to the wide variability of symptoms, the clinical diagnosis is very difficult and it is often made only years or even decades after the initial presentation. CASE REPORT - A 51-year-old Caucasian race man was admitted to the hospital with weigth loss and signs of subileus, referred for suspected lymphoma. After the exploratory laparotomy and lymphadenectomy the histological and the electron microscopical diagnosis was Whipple’s disease which was confirmed with histology from deep duodenal biopsy. Trimethoprim and sulfamethoxazole therapy for 6 months resulted in complete clinical and molecular biological healing. CONCLUSION - Clinical signs of Whipple’s dease are non-specific and may mimic Crohn’s disease, coeliac disease, amyloidosis, macroglobulinaemia, histoplasmosis, infection with non-tuberculotic mycobacterium in AIDS patients and lymphomas. Therefore, differential diagnosis is of critical importance. The natural evolution of the disease without treatment is always fatal. Trimethoprim and sulfamethoxazole for at least 1 year is usually considered adequate to eradicate the infection.]

Lege Artis Medicinae

MAY 16, 2007



[Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs worldwide. Gastroduodenal ulcers are found at endoscopy in 15 to 30% of patients who use NSAIDs regularly. The annual incidence of severe upper gastrointestinal complications such as bleeding or perforation is 1.0 to 1.5%. From a cost-benefit perspective, prevention strategies should consider both gastrointestinal, and recently, cardiovascular risk factors. No prophylaxis is necessary with low gastrointestinal risk. There are currently four possible strategies to reduce the risk of adverse gastrointestinal effects: 1. the use of selective COX-2 inhibitors or coxibs rather than traditional NSAIDs; 2. cotherapy, primarily with proton pump inhibitors, to ensure protection to gastric mucous membrane; 3. co-therapy with a coxib and a proton pump inhibitor in patients with very high risk (eg., history of bleeding); 4. eradication of Helicobacter pylori infection in patients with a history of ulcer. The use of coxibs decrease the risk of gastrointestinal damage by roughly 50%. In the presence of gastrointestinal risk factors or for patients on aspirin also treated with an NSAID or a coxib, protection with a proton pump inhibitor is recommended. Proton pump inhibitor therapy is also useful for the prevention and treatment of NSAID-induced dyspepsia. The beneficial effects of proton pump inhibitors cannot solely be explained by their profound antisecretory action. Therefore, several acid secretion- independent mechanisms of action have been proposed.]

Clinical Neuroscience

DECEMBER 10, 2004

[Early onset dementias: Case studies]

MERKLI Hajnalka, PÁL Endre, GÁTI István, KOSZTOLÁNYI Péter, KÖVÉR Ferenc

[Introduction - Dementia is a decline of intellectual abilities. The etiology of dementia syndrome is diverse. The authors describe three patients with early-onset dementia. Case reports - The first patient was a 44 years old male with mild gait, body ataxia, memory loss, slowness and apathy. Investigations proved AIDS dementia syndrome. In the second case of a 37 years old female patient, herpes simplex encephalitis was suspected due to sudden onset of speech arrest and to brain MRI and CSF findings. Her symptoms improved during antiviral treatment but later progressive dementia developed. CSF serological tests proved the presence of neurolues-dementia paralytica. The third patient was a 38-years-old female. Neurological examination was performed because of progressive memory loss, changed behaviour and impaired attention. Neuropsychological test showed severe dementia. Metachromatic leukodystrophy was proven by decreased arylsulfatase activity. Conclusions - It is not easy to recognize the early symptoms of dementia. In these cases, besides detailed history, neurological examination and neuropsychological tests, brain MRI and cerebral spinal fluid serological tests were indispensable for a correct diagnosis, especially in the young patients.]