Lege Artis Medicinae

[Transplantation in Hungary]

GÖRÖG Dénes

FEBRUARY 20, 2002

Lege Artis Medicinae - 2002;12(02)

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Lege Artis Medicinae

[9th Congress of the Hungarian Society for Hypertension and 11th Symposium on ABPM]

NAGY Viktor, SALLAI György

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[Comparison of piperacilline-tazobactam monotherapy with amikacine combined therapy in neutropenic patients with fever]

SZÉKELY Éva

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[The diagnosis and clinical impact of foramen ovale - The diagnostic criteria of paradoxical embolism]

LENGYEL Mária

Lege Artis Medicinae

[Aether]

KAPÓCS Gábor

Lege Artis Medicinae

[Data on health-behaviour in samples from counties with high and low suicide rates]

ZONDA Tamás, PAKSI Borbála

[Authors conducted a comparative sociological, social-psychiatric survey in the summer of 2000 on a representative sample (1000- 1000 people) from counties with high and low suicide rates (Bács-Kiskun and Vas). They also studied the so-called "health-behaviour" of subjects since it was supposed that negation or refusal of medical help are forms of latent auto-agressivity, probably of common origin with "direct" self-harm (alcohol abuse, smoking, suicide), from deeper behavioural roots. The rates of morbidity and mortality of the two counties do not differ each other significantly with the exception of alcoholism. In spite of this facts, people living in the Great Hungarian Plain (Alföld) regard themselves in worse health condition than people in western countryside, presenting as patients in the health care system more frequently in the Alföld. Authors did not find any connection between the quality of health behaviour and the sharply divergent suicide rates of the two territories. Studying the two sample as a whole, they found marked problems in the field of health behaviour in both counties. They also stress that suicide and alcoholism in Hungary are very closely connected entities. Authors suggest that tasks for the public health service in this matter are significant.]

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[Advanced Parkinson’s disease characteristics in clinical practice: Results from the OBSERVE-PD study and sub-analysis of the Hungarian data]

TAKÁTS Annamária, ASCHERMANN Zsuzsanna, VÉCSEI László, KLIVÉNYI Péter, DÉZSI Lívia, ZÁDORI Dénes, VALIKOVICS Attila, VARANNAI Lajos, ONUK Koray, KINCZEL Beatrix, KOVÁCS Norbert

[The majority of patients with advanced Parkinson’s disease are treated at specialized movement disorder centers. Currently, there is no clear consensus on how to define the stages of Parkinson’s disease; the proportion of Parkinson’s patients with advanced Parkinson’s disease, the referral process, and the clinical features used to characterize advanced Parkinson’s disease are not well delineated. The primary objective of this observational study was to evaluate the proportion of Parkinson’s patients identified as advanced patients according to physician’s judgment in all participating movement disorder centers across the study. Here we evaluate the Hungarian subset of the participating patients. The study was conducted in a cross-sectional, non-interventional, multi-country, multi-center format in 18 countries. Data were collected during a single patient visit. Current Parkinson’s disease status was assessed with Unified Parkinson’s Disease Rating Scale (UPDRS) parts II, III, IV, and V (modified Hoehn and Yahr staging). Non-motor symptoms were assessed using the PD Non-motor Symptoms Scale (NMSS); quality of life was assessed with the PD 8-item Quality-of-Life Questionnaire (PDQ-8). Parkinson’s disease was classified as advanced versus non-advanced based on physician assessment and on questions developed by the Delphi method. Overall, 2627 patients with Parkinson’s disease from 126 sites were documented. In Hungary, 100 patients with Parkinson’s disease were documented in four movement disorder centers, and, according to the physician assessment, 50% of these patients had advanced Parkinson’s disease. Their mean scores showed significantly higher impairment in those with, versus without advanced Parkinson’s disease: UPDRS II (14.1 vs. 9.2), UPDRS IV Q32 (1.1 vs. 0.0) and Q39 (1.1 vs. 0.5), UPDRS V (2.8 vs. 2.0) and PDQ-8 (29.1 vs. 18.9). Physicians in Hungarian movement disorder centers assessed that half of the Parkinson’s patients had advanced disease, with worse motor and non-motor symptom severity and worse QoL than those without advanced Parkinson’s disease. Despite being classified as eligible for invasive/device-aided treatment, that treatment had not been initiated in 25% of these patients.]

Lege Artis Medicinae

[Thiazide- or thiazide-like diuretics should be used in the treatment of patients with hypertension? Particularities of the situation in Hungary]

VÁLYI Péter

[Diuretics have remained the cornerstone of the antihypertensive treatment since their widespreading in the 1960s. According to the 2018 ESC/ESH Guidelines for the management of arterial hypertension, in the absence of evidence from direct comparator trials and recognizing that many of the approved single-pill combinations are based on hydrochlorothiazide, this drug and thiazide-like indapamide can be considered suitable antihypertensive agents. In the 2018 Hungarian guidelines indapamide is named as the most efficacious diuretic in the treatment of patients with hypertension. The aim of the publication is redefining thiazide- and thiazide-like diuretic use in the treatment of hypertensive patients, with particular attention to presently available hydrochlorothia­zide and indapamide, and their combination drugs in Hungary.]

Hungarian Radiology

[The quality control of radiological equipments in Hungary]

PELLET Sándor, PORUBSZKY Tamás, BALLAY László, GICZI Ferenc, MOTOC Anna Mária, VÁRADI Csaba, TURÁK Olivér, GÁSPÁRDY Géza

Clinical Neuroscience

[Organization of National Neurofibromatosis Register and fields of its application]

HORVÁTH András, FARKAS Viktor, LANGMÁR Zoltán, BACH Rezső, NAGY Zsolt B

[Background and purpose - The neurofibromatosis is a rare genetic disease with increased tumor growing ability and different special symptoms (Riccardi-criteria). The National NF Register has been organized by NF Hungary in 2011. The idea was initiated by hungarian neurofibromatosis experts. Methods - The register contains data about the therapists, the hospitals and the patients. The data are recorded by retrospective method and followed in time, so the register can track progress. Furthermore the register has valid nutrition, physical activity and psychological data, so the users are able to make comparisons with the clinical information. Results - 225 persons are registerd in the system on NF Hungary and 37 patients belong to the NF National Register. The number of the patients, who are member of the register, is always increasing. From the 37 persons 22 are females (60%) and 15 males (40%), 18 adults (48%) and 19 underagedes (52%). Conclusion - NF Register is a very useful system to do research and to draw public health and popolazione conclusions. The register enhances the morbidity details (time of manifestation, progressione, prognostical factors, prognosis), thereby could improve the cooperation and the coverage of the patients. The system is open for the patients as well, so it can give information to the patients about new scientific results, new medical methods and current availavable medications.]

Lege Artis Medicinae

[Why are the screening facilities in Hungary unexploited?]

DÖBRŐSSY Lajos, KOVÁCS Attila, DÖBRŐSSY Bence, BUDAI András, BONCZ Imre, MARGITAI Barnabás, KOÓS Tamás

[In Hungary, as a component of the National Public Health Programme, the “supply side” of the organised mass screening for early detection of some cancers has been established which would be capable of carrying out - in time periods set by the state-of-the-art - the regular screening of the population eligible by age. Unfortunately, the stated objectives of the programme have not fulfiled because the “demand side”, that is the compliance of the target population with the offered screening has remained far below the expectations. As a consequence, both the effectiveness and economic viability of the programme are damaged. The paper is to single out the possible causes: crudeness of concept of “organised screening”, the limited accessibility of sevices, anomalies of hralth care system, and, above all, some psychological side-effects of screening process.]