[The author’s response to the comment on “Exploratory study of outcomes of blood sample mass examinations by rank correlations”]
APRIL 18, 2020
Lege Artis Medicinae - 2020;30(04-05)
APRIL 18, 2020
Lege Artis Medicinae - 2020;30(04-05)
Szöveg nagyítása:
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Lege Artis Medicinae
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Lege Artis Medicinae
[Diabetes and depression are frequent comorbidities. They are a heavy burden by themselves, however, as comorbidities increase additionally the number of diabetes-related complications, morbidity, and mortality. In the background of interrelations, there are both well-known and hypothetical mechanisms. The aim of the present review is to outline these interrelations between antidepressants and diabetes and to discuss the effect of medications on carbohydrate metabolism respectively. Antidepressant treatment on the one hand may improve mood, cognitive function and medication adherence leading to an improved glucose metabolism, on the other hand through their metabolic side effects, they may worsen carbohydrate metabolism. Concerning metabolic side effects, selective serotonin reuptake inhibitors are the safest, while tricyclic antidepressants and monoamine oxidase inhibitors should be administered under close monitoring. Serotonin and noradrenaline reuptake inhibitors may deteriorate glycaemic control via increased noradrenergic activation. Novel antidepressants, however, have a neutral or positive impact on glycaemic measures. Screening for and temporally adjusted treatment of depression may decrease the risk of comorbidities generated complications. While caring for diabetic patients with depression, one should consider metabolic side effects of antidepressants and close monitoring of carbohydrate metabolism.]
Lege Artis Medicinae
[In the etiology of eating disorders (especially bulimia nervosa and binge eating) traumatic experiences (sexual, physical, emotional abuse, neglect) play an important role. Traumatization can have a serious impact, which is influenced by the parameters of the traumatization, risk and protective factors, and the resiliency of the traumatized patient. The consequences may lead to the development of specific psychiatric and somatic disorders, and may cause lifetime revictimization. The exploration of data related to the traumatization is essential in eating disorders as well. If traumatic expericences can be detected in the background of eating disorders, the targeted therapy of eating disorders while applying its specific elements should also follow the guidelines of the general trauma-therapy. Providing safety in therapeutical relationship is fundamental. The therapeutic options are extensive. Along with psychodynamically oriented therapies, the newer methods based on cognitive-behavioral therapy (e.g., dialectic behavior therapy, integrative cognitive analytic therapy) are also proposed. Hypnotherapy can also be useful. ]
Clinical Neuroscience
Atrial fibrilla- tion diagnosed after stroke (AFDAS) is a new term used for AF resulting from autonomic dysregulation. It is associated with a lower stroke recurrence compared to patients with known AF before a stroke (KAF). The aim of the study was to explore the characteristics and mortality rates in AFDAS patients. 134 ischemic stroke patients (66.1±14.2 years old, n=73 male) were consecutively included in the study.
Clinical Neuroscience
Natural disasters, such as earthquakes, frequently result in mood disorders among affected individuals. It is established that neuropathic pain arising from traumatic neuropathies is also linked to mood disorders. This study investigates the influence of neuropathic pain on the development of mood disorders in earthquake survivors with peripheral nerve injuries, following the earthquake centered in Kahramanmaraş on February 6, 2023.
Journal of Nursing Theory and Practice
[The purpose of the study is to find correlations between sarcopenia, falls, falls and social isolation in the elderly population.
This study chose a genre of literature review, in which seven articles were analyzed.
Weakness, falls and social isolation are closely related, which is also supported by statistical calculations.
The results of the literature review will help all professionals working in the care of the elderly to understand how different geriatric complex conditions are related to each other.]
Clinical Neuroscience
[Pain intensity is the most frequently assessed health domain in clinical studies among patients with low-back pain. Visual analogue scale (VAS) and Numeric rating scale (NRS) have been the mostly used measurement tools for pain intensity. We proposed to correlate these instruments to a generic health-related quality of life measurement tool in order to show the scale with superior clinical relevance.
We used cross-sectional, convenience sampling. 120 patients with chronic low-back pain administered the 29-item Patient Reported Outcomes Measurement Information System Profile with NRS included, and the VAS scale in the National Institute of Mental Health, Neurology and Neurosurgery. We determined the correlation between PROMIS domain T-scores and VAS and NRS scores.
We performed Spearman rank correlation test to calculate the correlation coefficient. We found VAS scales measuring pain had weak to moderate correlations with all PROMIS health domains (r = 0.24–0.55). Therefore, we compared correlation of PROMIS domain scores with PROMIS pain intensity numeric rating scale and VAS scales. PROMIS domains had moderate to strong correlations with pain intensity scale (r = 0.45–0.71). PROMIS physical function short form [r = –0.65, 95% CI (–0.75) – (–0.55)] and PROMIS pain interference short form (r = 0.71, 95% CI 0.63 – 0.79) had the strongest correlation with pain intensity item.
NRS has showed greater correlation with PROMIS domain T-scores than VAS scale. This may prove that NRS has greater connection to another health domains, thus it correlated more to health-related quality of life than visual scale. We recommend NRS to use in further clinical studies conducted among patients with low-back pain.]
Clinical Neuroscience
The aim of this study is to comprehensively determine the types of affected fibers in Parkinson’s disease (PD) patients by employing nerve conduction studies (NCS), sympathetic skin response (SSR) examinations, and current perception threshold (CPT) testing and to analyze the correlation between levodopa use and nerve involvement. This retrospective study included 36 clinically diagnosed PD patients who were recruited between January 2018 and April 2019.
Risk factors of posterior reversible encephalopathy syndrome in patients with preeclampsia or eclampsia: A retrospective review
Effect of surgical mask and N95 respirator mask use on cerebrovascular reactivity
1.
Clinical Neuroscience
Is there any difference in mortality rates of atrial fibrillation detected before or after ischemic stroke?2.
Clinical Neuroscience
Neuropathic pain and mood disorders in earthquake survivors with peripheral nerve injuries3.
Journal of Nursing Theory and Practice
[Correlations of Sarcopenia, Frailty, Falls and Social Isolation – A Literature Review in the Light of Swedish Statistics]4.
Clinical Neuroscience
[Comparison of pain intensity measurements among patients with low-back pain]5.
Journal of Nursing Theory and Practice
[Fear of Falling among Geriatric Patients: a Narrative Review]1.
Clinical Neuroscience
Recurrent simultaneous central nervous system demyelination with possible peripheral demyelination / nodopathy in a seronegative patient2.
3.
Clinical Neuroscience
Predictors of pneumonia in stroke patients with dysphagia: A Turkish study4.
5.
Clinical Neuroscience
Effect of inflammatory response before mechanical thrombectomy on prognosis in stroke patients
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