Lege Artis Medicinae

[Predicting restenosis after coronary angioplasty by very early dobutamine stress test]

VÉRTES András1, KOLONICS István1, NAGY András1, HANKÓCZY Judit1, PALIK Imre1, KELTAI Mátyás1

JUNE 30, 1992

Lege Artis Medicinae - 1992;2(06)

[Increasing dose of intravenous dobutamine infusion and bicycle exercise test was used in patients with angina pectoris before and after successful coronary angioplasty to predict the development of restenosis. Ten patients were enrolled (mean age 55.9). Before PTCA, DST was positive in 9 of the 10 patients. This was similar during maximal bicycle exercise test. After successful PTCA, DST remained negative in one, became negative in four, and remained positive in five patients. The day after PTCA (and DST), repeated coronary arteriography did not disclose significant residual or restenosis in any case. In one patients with positive early DST, symptomatic restenosis developed three days later. Follow-up coronarography was performed 6 months later. There were two patients with significant restenosis and one patients with remote progression of CAD. All of them had demonstrated a positive early DST. There was no restenosis at 6 months in the group of patients with negative early DST. The authors concluded that DST is suitable for detecting myocardial ischemia in single vessel disease; DST is safe immediately after PTCA; the risk of the development of restenosis is low if DST is negative after PTCA, while a positive recoronarography and redilatation may be advised in the latter group of patients. ]

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