Lege Artis Medicinae

[History of domestic medical administration]


OCTOBER 30, 1991

Lege Artis Medicinae - 1991;1(16)

[There is a lack of knowledge among the professional public about the older ways of health and medical administration in Hungary, although a review of the historical process can provide many lessons for today. Its first forms emerged in the Middle Ages, mainly in towns and densely populated villages, where the administrative bodies implemented the measures they took to ensure cleanliness and prevent epidemics, either themselves or through the offices they set up. They could even use the means of coercion, although their activities became truly effective when they were headed by professionals skilled and trained in the field of medicine.]



Further articles in this publication

Lege Artis Medicinae

[Cardiac rehabilitation a review]

VICTOR Froelicher, CRES P. Miranda

[The questions of cardiac rehabilitation are reviewed evaluating own personal experiences and pertaining current literature. The authors touch upon the question of early mobilization, as well as supervised and non supervised exercise. The criteria for the implementation of coronary angiography and acute revascularization procedures in the early phase of myocardial infarction are established. They review the secondary prevention of myocardial infarction and the effects of rehabilitation training on the patients prognosis.]

Lege Artis Medicinae

[Problems of organ transplantation - donor care]


[The development of the definition of brain death which is fundamental in cadaver organ removal for transplantation purposes is reviewed. Brain stem death, an alternative term for brain death is based primarily on clinical findings namely the irreversible cessation of cephalic reflexes and spontaneous breathing. Hypothermia, metabolic and endocrine abnormalities, prolonged muscle relaxant, sedative or hypnotic drug action should be excluded. The early recognition of potential donor and the maintenance of basic life function at the Intensive Care Unit and the operating theater are essential for the good function of the transplanted organs. Normal homeostasis should be maintained by ensuring adequate fluid intake, good circulation and urine output. Brain death potential donors can exhibit persistent spinal reflexes and spontaneous movement wich may be erroneously interpreted as signs of life. The problem of the determination of brain death under 4 year of age is also discussed although law does not allow to use them as potentional donors in Hungary. ]

Lege Artis Medicinae

[A review of a three year period in general practice]


[The author summarizes his work as a general practicioner in a village of 2000 people. He aimed to construct racional conditions of health care using technical, educational and organizing tools. Patients are reported to be satisfied and positive tendencies appeared in medicamentum consumption, and the number of sick days decreared from 13 673 to 10 198 per year. Less consultations of specialists and ask for hospital admission war performed. Indispensability of computers in the management of general practice is stressed. ]

Lege Artis Medicinae

[Having got a district]


[A beginner young general practicioner summarizes the experiences of his first year of work. Complex preparation for this work at the university, and the build up of the new practice of basic health service is described. Care of hypertension and diabetes is detailed, as an example how important and difficult is to reorganise this part of the work. The first year of experience gives a good possibility to look over the lack of undergraduate teaching This type of data collection and critical analysis seems to be necessary for a better planning of the forthcoming medical work. ]

Lege Artis Medicinae

[Chlamydia Pneumoniae: a new respiratory disease]

MARTON Anna , FÓRIS Katalin, SZALKA András, KÁROLYI Alice

[Current knowledge of Chlamydia pneumoniae, a newly recognized Chlamydia species that causes acute respiratory infection is summarized. Microbiology, classification and the laboratory diagnosis of the organism are discussed. Serological studies in Hungary suggest that almost everyone is infected during lifetime and reinfection is common as well. The organism appears to spread from human to human. Tetracyclin or erythromycin is recommended for the treatment of the Chlamydia pneumoniae infection. ]

All articles in the issue

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Fluoxetine use is associated with improved survival of patients with COVID-19 pneumonia: A retrospective case-control study

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We aimed to investigate the association between fluoxetine use and the survival of hospitalised coronavirus disease (COVID-19) pneumonia patients. This retrospective case-control study used data extracted from the medical records of adult patients hospitalised with moderate or severe COVID-19 pneumonia at the Uzsoki Teaching Hospital of the Semmelweis University in Budapest, Hungary between 17 March and 22 April 2021. As a part of standard medical treatment, patients received anti-COVID-19 therapies as favipiravir, remdesivir, baricitinib or a combination of these drugs; and 110 of them received 20 mg fluoxetine capsules once daily as an adjuvant medication. Multivariable logistic regression was used to evaluate the association between fluoxetine use and mortality. For excluding a fluoxetine-selection bias potentially influencing our results, we compared baseline prognostic markers in the two groups treated versus not treated with fluoxetine. Out of the 269 participants, 205 (76.2%) survived and 64 (23.8%) died between days 2 and 28 after hospitalisation. Greater age (OR [95% CI] 1.08 [1.05–1.11], p<0.001), radiographic severity based on chest X-ray (OR [95% CI] 2.03 [1.27–3.25], p=0.003) and higher score of shortened National Early Warning Score (sNEWS) (OR [95% CI] 1.20 [1.01-1.43], p=0.04) were associated with higher mortality. Fluoxetine use was associated with an important (70%) decrease of mortality (OR [95% CI] 0.33 [0.16–0.68], p=0.002) compared to the non-fluoxetine group. Age, gender, LDH, CRP, and D-dimer levels, sNEWS, Chest X-ray score did not show statistical difference between the fluoxetine and non-fluoxetine groups supporting the reliability of our finding. Provisional to confirmation in randomised controlled studies, fluoxetine may be a potent treatment increasing the survival for COVID-19 pneumonia.

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Late simultaneous carcinomatous meningitis, temporal bone infiltrating macro-metastasis and disseminated multi-organ micro-metastases presenting with mono-symptomatic vertigo – a clinico-pathological case reporT

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