Lege Artis Medicinae

[Gene modified immune cells: New weapons not exclusively against cancer]

SZÖŐR Árpád1

OCTOBER 21, 2020

Lege Artis Medicinae - 2020;30(10)

DOI: https://doi.org/10.33616/lam.30.036

[The oncological breakthrough of the last decade was the application of CD19-specific CAR T cells in different hematologic diseases. Experience gained by clinical trials, coupled with investments of the private stakeholders and the pharmaceutical industry resulted not only in commercial release to the public of already developed CAR T cell products, but drew the atten­tion of many researchers to the potentials of new type immune cells, and their non-oncological administration. This study aims to present briefly those preclinical applications, which approved successfully the administration of CAR T cells in autoimmune and infectious diseases.]

AFFILIATIONS

  1. Debreceni Egyetem, Általános Orvostudományi Kar, Biofizikai és Sejtbiológiai Intézet

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