Lege Artis Medicinae

[BENIGN SOLITER FIBROTIC TUMOR OF THE PLEURA - A CASE REPORT]

BOHÁCS Anikó, TAMÁSI Lilla, SOMOSKÖVI Ákos, MÉSZÁROS Zsolt, SÁPI Zoltán, BÁRTFAI Zoltán

NOVEMBER 21, 2004

Lege Artis Medicinae - 2004;14(11)

[INTRODUCTION - Rare asymptomatic pleuropulmonary neoplasms can represent serious differencial diagnostic difficulties both for clinicans and pathologists. Immunohistochemical tests are essential tools for the diagnosis of soliter fibrotic tumor of the pleura. These tests are also of diagnostic and prognostic importance. CASE REPORT - The report summarizes the case of an asymptomatic 63 years old man. The patient was admitted to hospital with a parahilar infiltrate of the right lung. Based on this chest X-ray abnormality pulmonary malignancy was suspected. The patient was referred to surgical intervention and the diagnosis of was based on post-surgical histology. These fibrotic tumors have typical immunohistochemical features. Although the histomorphology of the tumor suggested the presence of a benign tumor the p53 positivity and focal CD34 positivity indicated the possibility of malignant transformation as well. The patient is alive 17 months after surgery and there is no relapse of the disease. CONCLUSION - Although histologically benign, soliter fibrotic tumors of the pleura may occasionally transform into malignant variants. Therefore complete surgical resection and longterm clinical and close radiological follow-up is recommended for these patients. Clinician can plan well ahead the frequency and time of the follow-up with the help of the prognostic factors of hystology.]

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Lege Artis Medicinae

[LIPID-LOWERING THERAPY BASED ON RISK ASSESSMENT]

PARAGH György, BALOGH Zoltán

[The authors’ brief review follows the changes made to therapeutic guidelines based on primary and secondary prevention trials. They describe the main characteristics of National Cholesterol Education Program Adult Treatment Panel-I (NCEP ATP-I), ATP-II and ATP-III, and the decisions of the Hungarian Consensus Conference with respect to the lowering of lipids. The authors highlight the clinical importance of the evaluation of cardiovascular risk factors before the commencement of lipid-lowering therapy. They emphasize the significance of achieving the target values for low-density lipoprotein. Current dyslipidemia treatment guidelines focus on determining coronary heart disease risk status and matching the intensity of plasma LDL-C reduction to that perceived risk. Adding plasma C-reactive protein measurement to current risk assessment techniques may improve the identification of patients in the primary prevention population who may require more aggressive lipid-lowering therapy.]

Lege Artis Medicinae

[CHARACTERISTICS OF AUTOIMMUNE DISEASES]

SZEGEDI Gyula

[In the article the author reviews some features of autoimmune diseases and defines autoimmunity and autoimmune disease. According to epidemiological data, the number of patients increases and the causes are discussed in this paper. The pathogenetical background, the characteristics of the loss of immunetolerance are detailed. The author deals with the features of the pathomechanism, the course of the diseases and with the problems of the progression and classification. He also presents the expectations of clinicians to molecular medicine.]

Lege Artis Medicinae

[PHYSICAL AND PSYCHOLOGICAL CONDITION OF HEALTH CARE WORKERS DEALING WITH THE SERIOUSLY ILL]

HEGEDÛS Katalin, RISKÓ Ágnes, MÉSZÁROS Eszter

[INTRODUCTION - Health care professionals undertaking treatment/nursing of the seriously ill are equally overburdened emotionally, intellectually and physically. This condition might have several, sometimes irreversible negative consequences: avowed difficulties within the communication with patients, families and colleagues, various harms of accumulating, unprocessed stress, severe physical and psychological symptoms of mental burn-out which is very frequent and failures and difficulties of the private life. In our survey we aimed to gain a realistic image of the physical and psychological condition and quality of life of professionals working in Hungarian clinical care in order to provide with indelayable help. METHODS - The basis of the survey was a version of the Hungarostudy 2002 questionnaire, modified for health care professionals. In our sample there were 200 health care professionals dealing with seriously ill and in the control groups 1356 non health care professionals, and 227 health care professionals, choosen from the Hungarostudy survey. In all three groups the proportion of gender, age and education were the same. The results were analysed by the SPSS 10.0 statistical program and the relationship analysis was completed by ANOVA test. RESULTS - The analysis of the answers of those attending in our questionnaire survey - compared to those working in other health care field and to the control group of non health care workers - proves that the ratio of exhaustion and stress-dependent physical and psychological symptoms are prominently, in many cases significantly higher among health care workers dealing with the seriously ill, addiction is more frequent and social net is more unfavourable. These data are even worse for nurses than for doctors and other graduates. CONCLUSION - In treating difficult cases we can start to help with special education that should be general both in gradual and postgradual training.]

Lege Artis Medicinae

[Amongst the guilty, the silent is a pander - Consequences of research and publication misdemeanours]

VARRÓ Vince

Lege Artis Medicinae

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MATOS Lajos

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