Hypertension and nephrology

[The efficiency of angiotensin receptor blocker/neprilysin inhibitor (ARNI) treatment in heart failure 2021 ARNI, VIDI, VICI…]

VÁRALLYAY Zoltán1, KÉKES Ede2

APRIL 22, 2022

Hypertension and nephrology - 2022;26(02)

DOI: https://doi.org/10.33668/hn.26.010

[A new compound ARNi (valsartan/sacubitril) – as a member of a new pharmacoterapeutic group – has several clinical evidences almost in the whole spectrum of heart failure, especially in case of reduced left ventricular ejection fraction and hypertension. The most important and essential evidence based studies and the efficiency of the treatment with ARNI in heart failure have been demonstrated in this overview. Due to the favorable results of the studies the recommendations of ARNI indication are increasingly dominant in the clinical guidelines. The usage provides effective, safe therapeutic help for the poor life expectancy heart failure patients in the everyday clinical practice. The treatment is already available in Hungary.]

AFFILIATIONS

  1. Karolina Kórház, Belgyógyászati Mátrix Kardiopulmonológiai Egység, Hypertonia Minősített Szakambulancia, Mosonmagyaróvár
  2. Pécsi Tudományegyetem, Általános Orvostudományi Kar, Klinikai Központ, Kardiológiai Tanszék, Pécs

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[A new compound ARNi (valsartan/sacubitril) – as a member of a new pharmacoterapeutic group – has several clinical evidences almost in the whole spectrum of heart failure, especially in case of reduced left ventricular ejection fraction and hypertension. The most important and essential evidence based studies and the efficiency of the treatment with ARNi in heart failure have been demonstrated in this overview. Due to the favorable results of the studies the recommendations of ARNi indication are increasingly dominant in the clinical guidelines. The usage provides effective, safe therapeutic help for the poor life expectancy heart failure patients in the everyday clinical practice. The treatment is already available in Hungary.]

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