Hypertension and nephrology

[Evaluation of affective temperaments in healthy controls and in different hypertension phenotypes]

GYÖNGYÖSI Helga1, KŐRÖSI Beáta Zita1, BATTA Dóra1, LÁSZLÓ Andrea2, KOVÁCS Illés3, TISLÉR András4, CSEPREKÁL Orsolya5, NEMCSIK-BENCZE Zsófia6, GONDA Xénia7,8,9, RIHMER Zoltán7,10, NEMCSIK János1,11

JULY 05, 2022

Hypertension and nephrology - 2022;26(03)

DOI: https://doi.org/10.33668/hn.26.015

[Affective temperaments (depressive, anxious, irritable, hyperthymic and cyclothymic) are stable parts of personality and describe the emotional reactivity for external stimuli. Their relation to psychopathological conditions is obvious, and increasing amount of data is available in cardiovascular disorders. The aim of this study was to evaluate affective temperaments in healthy subjects (Cont), in white-coat hypertensive (WhHT), in non-resistant (non-ResHT) and in resistant hypertensive (ResHT) patients. In this cross-sectional study, 363 patients were included: 82 Cont, 44 WhHT, 200 non-ResHT and 37 ResHT. The patients completed the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire (TEMPS-A). In ResHT cyclothymic affective temperament points (4 [2.25–8]) were higher (p<0.05) compared with Cont (2 [0–5]) and with non-ResHT (3 [1–5]). Cyclothymic temperament points of WhHT (4 [2–7]) were also higher compared with Cont. ResHT was independently associated with cyclothymic scale equal or above 6 (Beta=2.59 [95% CI: 1.16–5.77]), irritable scale equal or above 7 (Beta=3.17 [95% CI: 1.3–7.69]) and anxious scale equal or above 9 (Beta=2.57 [95% CI: 1.08–6.13]) points. WhHT was also independently associated with cyclothymic scale equal or above 6 points (Beta= 2.378 [95% CI: 1.178–4.802]). In conclusions, white-coat and resistant hypertensive patients have specific affective temperament patterns, and their evaluation can help to understand the psychopathological background of these conditions.]

AFFILIATIONS

  1. Semmelweis Egyetem, Családorvosi Tanszék, Budapest
  2. Norisana – Praxis Rosenau, Bingstraße 30, Nürnberg, Németország
  3. Semmelweis Egyetem, Szemészeti Klinika, Budapest
  4. Semmelweis Egyetem, Belgyógyászati és Onkológiai Klinika, Budapest
  5. Semmelweis Egyetem, Sebészeti, Transzplantációs és Gasztroenterológiai Klinika, Budapest
  6. Semmelweis Egyetem, Orvosi Képalkotó Klinika, Budapest
  7. Semmelweis Egyetem, Pszichiátriai és Pszichoterápiás Klinika, Budapest
  8. Semmelweis Egyetem, Gyógyszerhatástani Intézet, Budapest
  9. MTA-SE Neuropszichofarmakológiai és Neurokémiai Kutatócsoport, Budapest
  10. Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet, Budapest
  11. Zuglói Egészségügyi Szolgálat (ZESZ), Budapest

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