Clinical Neuroscience

[Systemic thrombolysis after the administration of idarucizumab in acute ischemic stroke]

PÁSZTOR Máté1, BERECZKI Dániel1, SZAKÁCS ZOLTÁN1, MAY Zsolt1

JULY 30, 2017

Clinical Neuroscience - 2017;70(07-08)

DOI: https://doi.org/10.18071/isz.70.0284

[Introduction - Expanding indications have resulted in an increasing number of patients taking novel oral anticoagulants, posing a major treatment dilemma in acute ischemic stroke. Case presentation - We present a successful intravenous thrombolysis in a dabigatran-treated patient with acute ischemic stroke after the administration of idarucizumab. Discussion - According to current guidelines, systemic thrombolysis is contraindicated under treatment with novel oral anticoagulants (taken within 48 hours). In this scenario, idarucizumab offers a solution by reversing the anticoagulant effect of dabigatran. Conclusion - Although there have only been case reports published so far, the dabigatran-antidote idarucizumab seems to give new therapeutic opportunities in the treatment of acute ischemic stroke.]

AFFILIATIONS

  1. Magyar Honvédség Egészségügyi Központ, Neurológiai Osztály, Budapest

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Clinical Neuroscience

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Clinical Neuroscience

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Clinical Neuroscience

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