Clinical Neuroscience

[Recent studies in panencephalitis II. Electrophysiological observations]

GOMBI Róza1, ÓVÁRY Imre1, GŐDÉNY Sára1, SORSZEGI Pál1, KAPPÉTER István1, BENKŐ Károly1

SEPTEMBER 01, 1969

Clinical Neuroscience - 1969;22(09)

[Our electrophysiological observations are in agreement with the literature, according to which the Radermecker complex is a multifocal phenomenon, predominantly arising and manifesting in the cortex and at the border of the cortical white matter (Cobb 1966, Bogacz et al. 1959, etc.). This is suggested by the fact of multiple intracerebral phase reversals and the regional appearance or absence of complexes, which we observed in our patient. Intracerebral drainage has been performed very rarely in patients with panencephalitis, and the data obtained are similar to ours. Authors who have studied deep eletrography do not confirm the hypothesis of a thalamic - diencephalic origin of the complexes. In the opinion of Bogacz et al., the complexes are similar to the 'isolation complexes' (Garcia Austt et al. 1957) of partially or completely isolated cortex, in other words, to the 'suppression-burst' complexes (Henry and Scoville 1962). As the panencephalitic disease process progresses, neurons in the cortex and other structures become partially or completely deafferented, and there is a tendency and potential for hypersynchronous abnormal activity of deafferented cells after the loss of the tone or excitatory state necessary for normal function, provided by impulses from specific and non-specific pathways.]

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  1. DOTE Ideg- és Elmegyógyászati Klinika

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Further articles in this publication

Clinical Neuroscience

[The relationship between kappa rhythm and temporal paroxysms]

HASZNOS Tivadar

[By kappa rhythm, we mean the potentials induced by the 9-12/sec. count in the temporal derivation. The interpretation of kappa waves is still not uniform. Darow et al. and Kennedy et al. regard it as an artificial rhythm, or at least as a rhythm which is never considered as a separate temporal rhythm on its own. According to their hypothesis - and this is supported by a number of studies - intense mental work is accompanied by an increase in muscle tone, which would also entail, among other things, the vibration of the eye-coils, and the latter would manifest itself as a kappa rhythm. ]

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[Data for the assessment of pneumoencephalograms (Diencephalosis and ventricular dilatation)]

VÁRNAI György, PEKÁR Aranka, SZEGEDY László, HAITS Géza

[Authors analysed pneumoencephalography recordings of 270 unselected patients with identical radiological and approximately identical insufflation technique conditions for the correlation of lateral chamber index, ventricular index III, and absolute values of lateral chamber and ventricular dilatation III. In 49 of their 49 patients with the symptom complex of ,,diencephalosis" (,,hypothalamopathy"), isolated or prevalent III ventricular dilatation was found in 24.4% (12 patients), whereas in 20.3% (45 patients) of their 221 non-diencephalotic patients, the above findings were obtained. They analyse in detail the criteria for the evaluation of ventricular dilatation and urge caution regarding the resulting diagnostic conclusions.]

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[Genetic significance of muscle enzymes]

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[Enzyme assays were performed in patients with recessive x-linked dystrophia musculorum progressiva in four families and their family members. From a genetic point of view, the measurement of KFK activity is considered to be the most valuable. The method is well suited for the detection of vectors and in the preclinical phase of dystrophia musculorum progressiva.]

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[The authors performed qualitative protein analysis of cerebrospinal fluid from a Hungarian RADELKISZ-type polarograph in 158 patients. The criteria for normal curves were determined under the conditions described. An attempt was made to classify the abnormal curves and compare them with certain disease types. Lower than normal curves were obtained in endogenous psychoses and higher than normal curves in arteriosclerotic dementias, despite the fact that the protein content was within normal limits.]

Clinical Neuroscience

[Data on o-Toluidines and enzymatic liquor-sugar determination]

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[From comparative tests of O-Toluidines and enzymatic CSF sugar determination, the values obtained with the two methods did not show any significant difference. Given circumstances and options dictate which method is used for routine testing. For experimental tests, the enzymatic method is the appropriate method.]

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