Clinical Neuroscience

[Periodic paroxysmal discharges with occlusion of the middle cerebral artery]

HALÁSZ Péter1, GŐDÉNY Sára1, HIDASI János1

JANUARY 01, 1969

Clinical Neuroscience - 1969;22(01)

[Cerebral aneurysms due to a hemispherical occlusion of the middle cerebral artery develop a specific EEG activity, consisting of alternating discharges, some of which are single periodic paroxysmal discharges and others which are a series of discharges connected by flat segments. Based on the functional specificity of the electrical phenomena and the electropathological correlations, the two types of alternating activity observed in this patient can be analogized with the two main types of periodic paroxysmal phenomena; suppression-burst activity showing periodic complexes (panencephalitis-like) and cortical denervation pattern. A common pathomechanism can be discerned in these EEG phenomena, in which the specific metabolic state of the vascularly damaged and denervated cortex plays a crucial role. ]

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  1. Debreceni Orvostudományi Egyetem Ideg- és Elmegyógyászati Klinika

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Clinical Neuroscience

[Autoimmune aspects of myasthenia gravis]

SZOBOR Albert, BOZSÓKI Sándor, GÁSPÁRDY Géza

[Recent research suggests that an autoimmune process may also play a role in the pathomechanism of myesthenia gravis. In our own studies, 45 patients with myasthenia were serologically tested for antibodies against striated muscle, anti-gammaglobulin factor and anti-thyroid antibodies, and 46.6% were found to have anti-muscle antibodies. No serological reactions against muscle were detected in 52 control subjects. The positivity of anti-muscle immune reactions showed no correlation with patient age, sex, clinical status, prognosis, thymus surgery or irradiation. There are several possibilities for interpreting the immune positivity observed in myesthenia. One such possibility is the question of myasthenia beginning with respiratory tract infection, with a percentage approximately equal to the incidence of positive immune reactions and lymphorrhagia in muscle. The pronounced role of thymoma in the initiation of immune reactivity has not been established. Considering the possibility of a somatic mutation, the immunostimulatory role of the processes involved cannot be verified. The role of immune-serologically positive diseases associated with myasthenia is emphasized, based on the literature and our own material, but no explanation for the immunological implications of myasthenia is obtained based on disease association. Based on our studies, we outline our hypothesis that the immunobiological link of myasthenia is not causal and direct, but an indirect mechanism via the thymus. ]

Clinical Neuroscience

[Neurotic images in old age ]

HAITS Géza, TRINGER László, KŐMŰVES Géza

[Authors analysed the medical histories of 250 patients aged 55 to 75 years with neurosis, in whom vascular encephalopathy, other organic brain disease or psychotic symptoms could be excluded, who were first admitted to the Budapest Psychiatric Clinic between 1958 and 1966 and who had been treated for at least 2 weeks. They conclude: 1. that there is some correlation between age group and symptomatology, but it is not significant, 2. that there is no correlation between the underlying cause (conflict substance) and the nature of the symptomatology, but that the symptomatology is significantly related to premorbid personality and intellectual level. 3. the outcome of the syndrome is significantly related to a, the intellectual level, b, the age group, and c, the individual's activity level. ]

Clinical Neuroscience

[Acut isonicotinsav-hydrazid intoxicatio két esete]

OSTORHARICS György, BENCZE Miklós

[The authors report two successfully treated cases of acute INH intoxication. Among the explanations for the effects in the literature, they consider the nervous system and the general organ parenchymal damage to the liver to be the most important. The epileptic status epilepticus in the first seizure, as well as the diffuse cerebral laesio, reversible cerebral oedema, also detected by EEG, support the above pathomechanism. They wish to draw attention to the increasing prevalence of INH.]

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Late simultaneous carcinomatous meningitis, temporal bone infiltrating macro-metastasis and disseminated multi-organ micro-metastases presenting with mono-symptomatic vertigo – a clinico-pathological case reporT

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[Is the implementation of Vojta therapy associated with faster gross motor development in children with cerebral palsy? ]

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Clinical Neuroscience

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Clinical Neuroscience

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Clinical Neuroscience

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