Clinical Neuroscience

[Intramedullary epidermoid tumour]

DÉNES Iván1, ÁFRA Dénes1

AUGUST 01, 1966

Clinical Neuroscience - 1966;19(08)

[In our case, we did not find any data in the anamnesis that could be validated in favour of an exogenous implantation origin. The intramedullary location also argues against external implantation, as all intramedullary epidermoids are classified as congenital by the authors. Despite the onset of the disease in old age and the long course of the disease, our case must be classified as congenital, which emphasises the specificity and rarity of the case.]


  1. Orvostovábbképző Intézet Ideggyógyászati Tanszéke és az Országos Idegsebészeti Tudományos Intézet



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Clinical Neuroscience

[Data on myocardial myasthenia]


[The possibility of myasthenic involvement of the myocardium is discussed in a number of pathological reports and sporadic clinical literature, but the literature is not uniform. Our own review of casuistry provides no support for a specific understanding of cardiac dysfunction in patients with myasthenia; the cardiac histopathology findings of a patient who died of malignant myasthenia associated with thymoma were negative. The question may be related to the noncrisis-based mors subita in myasthenia; we have two patients of our own. Follow-up of each phase of thymectomy in a further two patients by recording the circulation and ECG to clarify the possibility of cardiac functio-alterations of a reflex nature. The possibility of myasthenic alterations of the myocardium is an open question. ]

Clinical Neuroscience

[Clinical experience with a new neuroleptic, Luvatren]

CZOPF József, KÉZDI Balázs

[A new butyrophenone derivative, Luvatren, was used to treat 18 inpatients and 2 outpatients, predominantly schizophrenics resistant to other treatments. 10 patients were discharged home as a result of treatment. The treatment was mainly effective in those with poor motivation, inhibition, negativism, incoherent thinking. In 4 cases we observed side effects (symptomatic Parkinsonism and collapsus-like malaise). ]

Clinical Neuroscience

[About neurological sarcoidosis]

MOLNÁR Sándor, ANNAU Magda

[The authors reported two cases of neurological sarcoidosis. The nature of the disease process in both cases was revealed by muscle biopsy examination. One case was a case of meningoencephalitis with psychiatric symptoms and the second case was a case of recurrent diabetes insipidus and motor neuron abnormalities. After describing the two cases, the authors presented the literature on neurological sarcoidosis, with some lessons learned.]

Clinical Neuroscience

[Study of changes in blood coagulation during carotid angiography]

LÁNG Sándor, AMBRÓZY György, HAITS Géza

[Authors studied the effect of contrast on blood clotting during carotid angiography in 50 cases. They found that the average amount of contrast agent given during carotid angiography had no appreciable effect on coagulation. ]

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Clinical Neuroscience

Extraskeletal, intradural, non-metastatic Ewing’s sarcoma. Case report


Intracranial localization of Ewing’s sarcoma is considerably very rare. Herein, we present clinical and neuroimaging findings regarding a 4-year-old boy with intracranial Ewing’s sarcoma. He was born prematurely, suffered intraventricular haemorrhage, posthaemorrhagic hydrocephalus developed, and a ventriculoperitoneal shunt was inserted in the newborn period. The patient endured re­gular follow ups, no signs of shunt malfunction nor increased intracranial pressure were observed. The last neuroima­ging examination was performed at 8 months of age. Upon reaching the age of 4 years, repeated vomiting and focal seizures began, and symptoms of increased intracranial pressure were detected. A brain MRI depicted a left frontoparietal space-occupying lesion infiltrating the superior sagittal sinus. The patient underwent a craniotomy resulting in the total excision of the tumour. The histological examination of the tissue revealed a small round blue cell tumour. The diagnosis was confirmed by the detection of EWSR1 gene translocation with FISH (fluorescent in situ hybridization). No additional metastases were detected during the staging examinations. The patient was treated in accordance to the EuroEwing 99 protocol. Today, ten years onward, the patient is tumour and seizure free and has a reasonably high quality of life.

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Clinical Neuroscience

Fatal outcome of cervical myelopathy caused by fibrocartilaginous embolism. Rare cause of spinal vascular damage

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Fibrocartilaginous embolism is a rare cause of ischemic myelopathy. Authors report a case of a 39-year-old woman with progressive tetraparesis and severe autonomic dysfunction. Despite of the detailed examinations, the definite diagnosis was verified by autopsy. The patient was admitted because of progressive pain and numbness of the upper extremities and tetraparesis. Hypotonic muscles of the lower extremities with mild tetraparesis were observed. Magnetic resonance imaging showed an intramedullary lesion at the level of the cervical V-VII vertebral. Patient’s tetraparesis worsened gradually to plegia with urinary retention. Expansive, rapidly progressing multiple decubiti developed, which were resistant to therapy. In spite of the complex therapy, the patient died. No internal disease was found to explain the death by autopsy. Multiple subacute infarctions of the cervical myelon (involving the lateral columns as well) in the territory of the anterior spinal artery were verified by neuropathological examination. The occluded vessels were filled by a material containing cartilaginous cells, while signs of atherosclerosis or thrombosis were not present. Cartilaginous embolism of spinal arteries was diagnosed.

Clinical Neuroscience

[Early experience with CyberKnife treatment in case of intra-, suprasellar hypernephroma metastasis]


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Clinical Neuroscience

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