Clinical Neuroscience

[Interhemispheric asymmetry of diffusion parameters in the human brain]

WALTER Norbert1, HORVÁTH Ildikó2, VANDULEK Csaba3, BERÉNYI Ervin4, BOGNER Péter1,3,5, TÓTH Lilla5

MARCH 25, 2009

Clinical Neuroscience - 2009;62(03-04)

[Our aim was to study the hemispheric asymmetry of the human brain through the simultaneous measurements of the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values within a homogeneous sample in regards to the gender, age and handedness. Method - Eleven young women were included in our diffusion study performed on a 1.5 T MR scanner. We calculated the ADC and FA values in nine-nine region of interest points of the brain. The diffusion values were measured symmetrically in the right and left hemisphere of the brain and were then statistically compared to detect interhemispheric asymmetry. Results - We did not find any significant differences between the data of the two hemispheres in regards to the ADC values. However, we detected a significant right sided asymmetry in case of the globus pallidus in FA values (p=0.04). Conclusion - Our results of our study of young women suggest that diffusion asymmetry does not appear in case of ADC values and only slightly (in one ROI in our study) in FA values.]

AFFILIATIONS

  1. Pécsi Tudományegyetem, Egészségtudományi Kar, Kaposvári Képzési Központ, Diagnosztikai Képalkotó Tanszék, Kaposvár
  2. Pécsi Tudományegyetem, Egészségtudományi Kar, Pécsi Képzési Központ, Biostatisztikai és Egészségügyi Informatikai Tanszék, Pécs
  3. Kaposvári Egyetem, Egészségügyi Centrum, Kaposvár
  4. Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Orvosi Laboratóriumi és Képalkotó Diagnosztikai Tanszék, Debrecen
  5. Kaposvári Egyetem, Diagnosztikai és Onkoradiológiai Intézet, Kaposvár

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