[During stress, the activation of the hypothalamus- pituitary-adrenal axis and the sympathetic, sensory nervous system leads to an increased production of glucocorticoids, catecholamines and other active peptides. The specific receptors on immunocompetent and tissue cells for glucocorticoid, corticotropin-releasing hormone and histamine, substance-P, norepinephrine, calcitonin gene-related peptide can modify the cytokine production of macrophages, lymphocytes and tissue cells. Local hormonal effects have a role in the degranulation of mast cells and thus in histamine release and neurogenic inflammation. Long-term, chronic inflammations promote carcinogenesis, in which the tumourassociated macrophages have an important role. Carcinogenesis is associated with disturbed cooperation between the neuronal immune and endocrine systems.]

[The relationship between stress and mental illness has been extensively studied and there is a growing consensus that the occurrence of mental illness rather depends on a combination of factors than is caused by stressful external events. Significant hypothalamus pituitary adrenal axis abnormalities were observed among others in major depressive disorder and bipolar disorder. In both disorders, the extent of change in cortisol level was related to the severity of illness and to cognitive changes. Exogenous use of synthetic steroids also frequently resulted in severe psychiatric symptoms. In conclusion changes in the level of steroid hormones may cause impairments in the brain.]

[Chronic stress is associated with increased levels of cortisol and catecholamines as well as with an enhanced activity of the sympathico-sensory nervous system. These neuroendocrine events influence both directly and indirectly the lipid and glucose metabolism as well as inflammatory immune reactions. Stress effects directly cause vascular damage and atherosclerosis via the renin-angiotensin system (RAS). Besides RAS, activities of monocytes/macrophages and the sympathico-sensory nervous system lead to local cardiovascular inflammation and cell hypertrophy. Transactivation between G-protein coupled adrenoceptors and tyrosine kinase receptors as well as the switching between β1- and β2- adrenergic receptors play an important role in the development of cardiac hypertrophy and heart failure. In all chronic neuroendocrine diseases that are associated with increased activity of the sympathetic nervous system, the development of cardiovascular damages needs to be considered.]

[The aim of the study: The objective of the study was to assess and compare job and life satisfaction affected by workplace problems, stress, rewards, success and social support. We analyzed the coping strategies applied by the employees to solves the above problems. Material and method: The anonymous data collection was carried out in October, 2015 by applying AVEM and an own-edited socio-demographic questionnaire among theatre nurses from Hungarian and German clinics. Results: The employees evaluated stressful situations and problems differently in the two groups examined. Job satisfaction was equally important for both groups, but it affected life satisfaction of the Hungarian employees to greater extent. The stress management of the Hungarian employees was more effective in spite of the fact that German nurses used more coping strategies. Social support had a positive effect on overcoming the workplace problems in both groups. Conclusions: Job satisfaction of the nurses has a beneficial effect on their life satisfaction. The ability to divide work and private life and stress management are different among the nurses. Job satisfaction can be improved by workplace health promotion programs.]

[The aim of the study is drawing the attention to the possibilities of applying musical tools in healing children. After doing research in main medical databases (PubMed, Web of Science, Medline) some research works were discovered and harmonized in which the researchers give proof of the effectiveness of music therapies implemented in therapeutic circumstances and by proper experts on medical fields. The study focuses on the following topics: applying music for reducing stress caused by medical interventions and hospitalization, treating speech disturbances, improving communication and social abilities of autistic children, improving capabilities of people suffering from visual and hearing impairment, providing help during anaesthesia, stimulating different parts of the brain in children suffering from PDOC (Prolonged Disorder of Consciousness), improving capabilities of children living with disabilities and helping creating harmonic relationship between children, their parents and the healing staff. ]