Clinical Neuroscience

[Extracranial electrostimulation I. Effect of electrostimulation on the eeg]

HASZNOS Tivadar1, FENYŐ Egon1, ANTAL János1

OCTOBER 01, 1963

Clinical Neuroscience - 1963;16(10)

[The authors used electrodes placed on the scalp to stimulate the scalp partly locally and partly bitemporally with rectangular current pulses. Local stimulation was also performed with bipolar electrode placement. The frequency of stimulation was varied between 2/sec and 10 000/sec and the duration between 0.03 msec and 100 msec. The applied voltage was usually 30 V. The stimulation lasted for 30 or 60 seconds. EEG recording was performed immediately after the end of stimulation. The tests were performed on 18 patients. In patients with tumours, an increase in slow activity and focal excitatory signals were observed in response to local stimulation. In temporal epilepsy an increase in focal symptoms and in post-traumatic patients an increase in slow focal activation were observed. In patients with centrencephalic epilepsy with bitemporal stimulation, centrencephalic paroxysms were seen, and in temporal epilepsy, local slow and excitatory activation of signs. The authors hypothesize that local stimulation is primarily used to stimulate cortical and cortical proximal structures, whereas bitemporal electrostimulation seems to be a suitable technique for stimulation of the mesodiencephalon. ]

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  1. Budapesti Orvostudományi Egyetem Neurológiai Klinika

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[Extra., intracranialis localised cavernosus haemangioma]

PÁSZTOR Emil, SZABÓ Gyula, SLOWIK Felicia, ZOLTÁN János

[ In a 36-year-old female patient, multiple cavernous haemangiomas were detected and histologically verified in the right cheek, right os parietalera and right skull base. The case cannot be classified as a multiple haemangiomatous syndrome (Willis), the lesions are localized to the right external carotid artery system. Two years previously, plastic surgery of the right facial skin was performed and currently a large non-bony tumour extending from the base of the skull into the intracranial space has been removed. We discuss the pathological, angiographic and surgical indicative aspects of cavernous haemangiomas of the skull bone in our case. ]

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[In humans, the more profound the anaesthesia, the more the "pure synchronisation" of the EEG responses to different peripheral stimuli becomes apparent. Biological signs of reduced sleep depth and pupil dilation are associated with a more sustained synchronisatio, which therefore corresponds to an "inverse" electrical manifestation of a coarse, limited arousal. However, as anaesthesia wears off, there is an increasing proportion of more rapid frequencies in the EEG responses. At first, desynchronised sleep stages appear in which the spontaneous EEG, bioelectrical and motor responses resemble the 1st (IV) stage of human spontaneous sleep and the "paradoxical" ("rhombencephalic") sleep stages of animals. The development of such "paradoxical" stages in humans is often facilitated by peripheral stimulus influx. Later on, bipartite (desynchronisatio + post-synchronisatio) responses are formed; the biological meaning and origin of "pure synchronisatio" and "post-synchronisatio" are not identical. The return of alert wakefulness occurs in the company of "pure desynchronisatio" responses. The generation of these response types is determined by states of functional disinhibition and restitution induced by anaesthesia, which reflect the relations of superiority and inferiority of dependence between reticular systems. The pupillomotor reactivity during barbiturate action is poor compared to the morphological sensitivity of the EEG; the synchronization induced by peripheral stimuli is accompanied by mydriasis, whereas the "paradoxical" phase is accompanied by miosis. The EDG is hyperactive during moderate barbiturate exposure but is rapidly extinguished by deepening anaesthesia; its return and increased excitability are linked to orientational responsiveness, minimal verbal contact ability and a phase of dual EEG responses.]

Clinical Neuroscience

[Constitution and Rules of the World Federation of Neurology (Fédération Mondiale de Neurologie). 1963. ]

[The author reports on the Constitution and Rules of the World Federation of Neurology (Fédération Mondiale de Neurologie). ]

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