Clinical Neuroscience

[Effect of Andaxin ( meprobamate) on skeletal muscle phosphorylase activity]

KOCSÁR László1, VERESS Olivia1, KAJTOR Ferenc1

MARCH 01, 1960

Clinical Neuroscience - 1960;13(03)

[1. The effect of Andaxin (meprobamate) on skeletal muscle phosphorylase activity of dogs, rats, rabbits and guinea pigs after 4-6 days of enteral meprobamate administration was investigated. 2. Our results show that after Andaxin treatment, the phosphorylase activity of dog muscle decreased by 25-73% (45% on average) and that of rat muscle by 19-56% (40%). 3. Rabbit muscle phosphorylase activity increased by -9.3 -( +170.0)% (43%) and guinea pig by 114% after Andaxin administration. 4. The phosphorylase activity of skeletal muscle of dog, rat, rabbit, guinea pig was not affected by Andaxin in vitro.]

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  1. Debreceni Orvostudományi Egyetem Kórélettani Intézetének Ideg-és Elmeklinikája

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[1. Based on a comparison of the symptoms of eight schizophrenic patients with ES block before and after treatment with 50- 125 gamma LSD, the change in response after treatment was analysed from a pathophysiological and localisation point of view. 2. ES block treatment did not completely prevent the development of LSD intoxication symptoms, but the reactio was strikingly poor. No activating effect was observed. 3. Symptoms partially corresponded to specific LSD symptoms. No cortex localisable intoxication symptoms developed. 4. Subcortical and midbrain symptoms were present. Brainstem movement disturbances and neurovegetative changes were suggestive of diencephalic dysregulation.]

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[Data for the biography of Ferenc Schwartzer]

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Clinical Neuroscience

[Comment on the article "The problem of remuneration for occupationally mentally ill people"]

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[The development of specific operating rules for institutions for the treatment of the mentally ill, different from those for hospitals, in line with their specific situation, and taking into account the following aspects: 1. in the case of rehabilitation institutions, economic profitability, with appropriate deductions for the remuneration of patients. 2. in the case of a therapeutic establishment, the therapeutic aspect, with the possibility of rewarding the patient in various ways for psychotherapeutic purposes and, at the same time, with appropriate social care. 3. formation of a joint committee of appropriate financial and mental health professionals to clarify various financial issues.]

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